Literature DB >> 16221475

Computational analysis of type II endoleaks in a stented abdominal aortic aneurysm model.

Z Li1, C Kleinstreuer.   

Abstract

Insertion of a stent-graft into an aneurysm to form a new (synthetic) blood vessel and prevent the weakened artery wall from rupture is an attractive surgical intervention when compared to traditional open surgery. However, focusing on a stented abdominal aortic aneurysm (AAA), post-operative complications such as endoleaks may occur. An endoleak is the net influx of blood during the cardiac cycle into the cavity (or sac) formed by the stent-graft and the AAA wall. A natural endoleak source may stem from one or two secondary branches leading to and from the aneurysm, labeled types IIa and IIb endoleaks. Employing experimentally validated fluid-structure interaction solvers, the transient 3-D lumen and cavity blood flows, wall movements, pressure variations, maximum wall stresses and migration forces were computed for types IIa and IIb endoleaks. Simulation results indicate that the sac pressure caused by these endoleaks depends largely on the inlet branch pressure, where the branch inlet pressure increases, the sac pressure may reach the systemic level and AAA-rupture is possible. The maximum wall stress is typically located near the anterior-distal side in this model, while the maximum stent-graft stress occurs near the bifurcating point, in both cases, due to local stress concentrations. The time-varying leakage rate depends on the pressure difference between AAA sac and inlet branch. In contrast, the stent-graft migration force is reduced by type II endoleaks because it greatly depends on the pressure difference between the stent-graft and the aneurysm cavity.

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Year:  2005        PMID: 16221475     DOI: 10.1016/j.jbiomech.2005.09.002

Source DB:  PubMed          Journal:  J Biomech        ISSN: 0021-9290            Impact factor:   2.712


  8 in total

Review 1.  Contemporary Role of Computational Analysis in Endovascular Treatment for Thoracic Aortic Disease.

Authors:  Guido H W van Bogerijen; Jip L Tolenaar; Michele Conti; Ferdinando Auricchio; Francesco Secchi; Francesco Sardanelli; Frans L Moll; Joost A van Herwaarden; Vincenzo Rampoldi; Santi Trimarchi
Journal:  Aorta (Stamford)       Date:  2013-08-01

2.  Experimental Analysis of Pressure and Flow Alterations During and After Insertion of a Multilayer Flow Modulator into an AAA Model with Incorporated Branch.

Authors:  Simon Tupin; Kei Takase; Makoto Ohta
Journal:  Cardiovasc Intervent Radiol       Date:  2021-04-27       Impact factor: 2.740

Review 3.  [Simulation of blood flow within the abdominal aorta. Computational fluid dynamics in abdominal aortic aneurysms before and after interventions].

Authors:  T Frauenfelder; E Boutsianis; H Alkadhi; B Marincek; T Schertler
Journal:  Radiologe       Date:  2007-11       Impact factor: 0.635

Review 4.  A literature review of the numerical analysis of abdominal aortic aneurysms treated with endovascular stent grafts.

Authors:  David Roy; Claude Kauffmann; Sébastien Delorme; Sophie Lerouge; Guy Cloutier; Gilles Soulez
Journal:  Comput Math Methods Med       Date:  2012-09-06       Impact factor: 2.238

5.  Fluid structure interaction of patient specific abdominal aortic aneurysms: a comparison with solid stress models.

Authors:  James H Leung; Andrew R Wright; Nick Cheshire; Jeremy Crane; Simon A Thom; Alun D Hughes; Yun Xu
Journal:  Biomed Eng Online       Date:  2006-05-19       Impact factor: 2.819

6.  Hemodynamic Study of Flow Remodeling Stent Graft for the Treatment of Highly Angulated Abdominal Aortic Aneurysm.

Authors:  Siang Lin Yeow; Hwa Liang Leo
Journal:  Comput Math Methods Med       Date:  2016-05-09       Impact factor: 2.238

7.  Fenestrated stent graft repair of abdominal aortic aneurysm: hemodynamic analysis of the effect of fenestrated stents on the renal arteries.

Authors:  Zhonghua Sun; Thanapong Chaichana
Journal:  Korean J Radiol       Date:  2009-12-28       Impact factor: 3.500

8.  Fluid-structure interaction of a patient-specific abdominal aortic aneurysm treated with an endovascular stent-graft.

Authors:  David S Molony; Anthony Callanan; Eamon G Kavanagh; Michael T Walsh; Tim M McGloughlin
Journal:  Biomed Eng Online       Date:  2009-10-06       Impact factor: 2.819

  8 in total

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