| Literature DB >> 16216454 |
Esra Küpeli1, Didem Deliorman Orhan, Erdem Yesilada.
Abstract
In this study, the effect of the flavonoids quercetin-3-methyl-ether (isorhamnetin) (1), quercetin-3,7-dimethyl-ether (2) and kaempferol-3,7-dimethyl-ether (3) isolated from Cistus laurifolius L. (cistaceae) leaves was assessed on lipid peroxidation (liver and plasma), cellular glutathione (GSH) level and plasma AST (aspartate aminotransferase), ALT (alanine aminotransferase) enzyme activities in acetaminophen-induced liver damage in mice. At 114 mg/kg oral dose quercetin-3,7-dimethyl-ether was shown to possess potent antioxidative activity.Entities:
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Year: 2005 PMID： 16216454 DOI： 10.1016/j.jep.2005.08.038
Source DB: PubMed Journal: J Ethnopharmacol ISSN： 0378-8741 Impact factor: 4.360