Literature DB >> 16215840

Canine epidermal langerhans cells express alpha and gamma but not beta chains of high-affinity IgE receptor.

M Bonkobara1, F Miyake, H Yagihara, O Yamada, D Azakami, T Washizu, P D Cruz, K Ariizumi.   

Abstract

Epidermal Langerhans cells (LC) express a high-affinity receptor for IgE (FcepsilonRI), consisting of two chains (alpha and gamma chains) in humans that allows LC to perform Fc receptor-mediated uptake of allergens. We found that canine LC express alpha and gamma chains but not beta chain of FcepsilonRI, identical to human but not to mouse LC, which do not express functional FcepsilonRI (only gamma chain is expressed). This finding indicates that canine LC have FcepsilonRI-mediated function similar to or identical to human LC, raising the possibility that canine species provides a better model than mouse to understand the pathogenesis of human atopic dermatitis and investigate the therapeutic effect of drugs.

Entities:  

Mesh：

Substances：

Year:  2005        PMID： 16215840     DOI： 10.1007/s11259-005-2494-7

Source DB:  PubMed          Journal:  Vet Res Commun        ISSN： 0165-7380            Impact factor:   2.459


  23 in total

Review 1.  Signalling through the high-affinity IgE receptor Fc epsilonRI.

Authors:  H Turner; J P Kinet
Journal:  Nature       Date:  1999-11-25       Impact factor: 49.962

2.  Molecular cloning of cDNAs encoding dog high-affinity IgE receptor alpha, beta, and gamma chains.

Authors:  R Goitsuka; N Hayashi; M Nagase; N Sasaki; C Ra; H Tsujimoto; A Hasegawa
Journal:  Immunogenetics       Date:  1999-06       Impact factor: 2.846

Review 3.  The ACVD task force on canine atopic dermatitis (V): biology and role of inflammatory cells in cutaneous allergic reactions.

Authors:  P B Hill; T Olivry
Journal:  Vet Immunol Immunopathol       Date:  2001-09-20       Impact factor: 2.046

Review 4.  How IgE upregulates the allergic response.

Authors:  Sarbjit S Saini; Donald MacGlashan
Journal:  Curr Opin Immunol       Date:  2002-12       Impact factor: 7.486

5.  Complete structure of the mouse mast cell receptor for IgE (Fc epsilon RI) and surface expression of chimeric receptors (rat-mouse-human) on transfected cells.

Authors:  C Ra; M H Jouvin; J P Kinet
Journal:  J Biol Chem       Date:  1989-09-15       Impact factor: 5.157

6.  Immobilization and internalization of mutated IgE receptors in transfected cells.

Authors:  S Y Mao; N Varin-Blank; M Edidin; H Metzger
Journal:  J Immunol       Date:  1991-02-01       Impact factor: 5.422

Review 7.  The ACVD task force on canine atopic dermatitis (XIV): clinical manifestations of canine atopic dermatitis.

Authors:  C E Griffin; D J DeBoer
Journal:  Vet Immunol Immunopathol       Date:  2001-09-20       Impact factor: 2.046

8.  Epidermal Langerhans cell-targeted gene expression by a dectin-2 promoter.

Authors:  M Bonkobara; P K Zukas; S Shikano; S Nakamura; P D Cruz; K Ariizumi
Journal:  J Immunol       Date:  2001-12-15       Impact factor: 5.422

9.  Langerhans cell hyperplasia and IgE expression in canine atopic dermatitis.

Authors:  T Olivry; P F Moore; V K Affolter; D K Naydan
Journal:  Arch Dermatol Res       Date:  1996-09       Impact factor: 3.017

10.  Regulation of the high affinity receptor for IgE on human epidermal Langerhans cells.

Authors:  S Kraft; J H Wessendorf; D Hanau; T Bieber
Journal:  J Immunol       Date:  1998-07-15       Impact factor: 5.422
View more
  3 in total

Review 1.  IgE immunotherapy against cancer.

Authors:  Lai Sum Leoh; Tracy R Daniels-Wells; Manuel L Penichet
Journal:  Curr Top Microbiol Immunol       Date:  2015       Impact factor: 4.291

2.  IgE-based Immunotherapy of Cancer -A Comparative Oncology Approach.

Authors:  Josef Singer; Erika Jensen-Jarolim
Journal:  J Carcinog Mutagen       Date:  2014-05-31

Review 3.  IgE-based immunotherapy of cancer: challenges and chances.

Authors:  J Singer; E Jensen-Jarolim
Journal:  Allergy       Date:  2013-10-14       Impact factor: 13.146
  3 in total

北京卡尤迪生物科技股份有限公司 © 2022-2023.