Literature DB >> 16215543

Tuberculosis: an under-diagnosed aetiological agent in uveitis with an effective treatment.

D Varma1, S Anand, A R Reddy, A Das, J P Watson, D C Currie, I Sutcliffe, O C Backhouse.   

Abstract

PURPOSE: To highlight the diversity of clinical presentations with tubercular uveitis in a nonendemic setting, and discuss the diagnostic approach and an effective treatment.
METHOD: Descriptive case series.
RESULTS: A total of 12 cases of varied presentations of tubercular uveitis diagnosed over a period of 1 year of which six cases are described in detail. Presentations included choroidal tuberculomas, multifocal choroiditis, recurrent granulomatous uveitis, panuveitis with cystoid macular oedema, and serpiginous choroiditis. All cases had a chronic or recurrent course and responded very well to antitubercular treatment. Diagnosis was mainly assisted by positive tuberculin testing.
CONCLUSION: A high index of suspicion helps diagnose ocular tuberculosis in areas of low prevalence of the disease. It forms part of the differential diagnosis of any chronic or recurrent uveitis, especially in an at-risk patient. Antitubercular treatment seems highly effective.

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Year:  2005        PMID: 16215543     DOI: 10.1038/sj.eye.6702093

Source DB:  PubMed          Journal:  Eye (Lond)        ISSN: 0950-222X            Impact factor:   3.775


  22 in total

1.  Anti-tuberculous therapy combined with systemic corticosteroids improves retinal sensitivity in patients with active presumed tuberculous choroiditis.

Authors:  Ahmed M Abu El-Asrar; Hani S Al-Mezaine
Journal:  Int Ophthalmol       Date:  2010-05-15       Impact factor: 2.031

2.  Orbital tuberculosis presenting as proptosis and fever: the risk of empiric corticosteroids.

Authors:  Rodrigo de Carvalho Santana; Paulo Louzada; Valdes Roberto Bollela; Antonio Augusto Vellasco Cruz; Benedito Antonio Lopes da Fonseca
Journal:  Int Ophthalmol       Date:  2013-03-10       Impact factor: 2.031

3.  Clinical presentation, treatment, and outcomes in presumed intraocular tuberculosis: experience from Newcastle upon Tyne, UK.

Authors:  K Manousaridis; E Ong; C Stenton; R Gupta; A C Browning; R Pandit
Journal:  Eye (Lond)       Date:  2013-02-22       Impact factor: 3.775

Review 4.  Serpiginous choroiditis and infectious multifocal serpiginoid choroiditis.

Authors:  Hossein Nazari Khanamiri; Narsing A Rao
Journal:  Surv Ophthalmol       Date:  2013-03-27       Impact factor: 6.048

5.  Presumed tuberculous uveitis: diagnosis, management, and outcome.

Authors:  C Sanghvi; C Bell; M Woodhead; C Hardy; N Jones
Journal:  Eye (Lond)       Date:  2011-02-04       Impact factor: 3.775

6.  Treatment outcome in patients with presumed tubercular uveitis at a tertiary referral eye care centre in Singapore.

Authors:  Leslie Ang; Aera Kee; Tun Hang Yeo; V G Dinesh; Su Ling Ho; Stephen C Teoh; Rupesh Agrawal
Journal:  Int Ophthalmol       Date:  2016-12-29       Impact factor: 2.031

7.  Ocular disorders in adult patients with tuberculosis in a tertiary care hospital in Nigeria.

Authors:  E E Egbagbe; A E Omoti
Journal:  Middle East Afr J Ophthalmol       Date:  2008-04

Review 8.  Anti-tubercular therapy for intraocular tuberculosis: A systematic review and meta-analysis.

Authors:  Ae Ra Kee; Julio J Gonzalez-Lopez; Aws Al-Hity; Bhaskar Gupta; Cecilia S Lee; Dinesh Visva Gunasekeran; Nirmal Jayabalan; Robert Grant; Onn Min Kon; Vishali Gupta; Mark Westcott; Carlos Pavesio; Rupesh Agrawal
Journal:  Surv Ophthalmol       Date:  2016-03-10       Impact factor: 6.048

Review 9.  [White dot syndrome].

Authors:  W Göbel
Journal:  Ophthalmologe       Date:  2008-01       Impact factor: 1.059

10.  Experimental ocular tuberculosis in guinea pigs.

Authors:  Narsing A Rao; Thomas A Albini; Mirnalini Kumaradas; Michael L Pinn; Mostafa M Fraig; Petros C Karakousis
Journal:  Arch Ophthalmol       Date:  2009-09
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