Literature DB >> 16214227

Rhino-bronchial syndrome in children: pathogenic correlations and clinical-experimental aspects.

Michele Cassano1, Pasquale Cassano, Mappa Luigi, Matteo Gelardi, Aline Castelante Farràs, Maria Luisa Fiorella.   

Abstract

OBJECTIVE: This study aims at defining the incidence of rhino-bronchial syndrome (RBS) in children in order both to verify the influence of nasal obstructions on the disease and to determine therapeutic strategies which may cure the syndrome effectively at its early stage.
METHODS: The investigation includes 128 non-allergic children with obstructive disorders (adenoid hypertrophy, septal deviation, etc.) and rhino-sinus inflammations associated with bronchopulmonary diseases (asthma, chronic cough, bronchopulmonary infections). Medical and/or surgical treatment was chosen in consideration of the type and entity of the patients' main nasal pathology. At least 1 year follow-up was provided for each case to establish the improvement in the disorders affecting both the lower and upper airways. The results were statistically assessed.
RESULTS: Medical and mainly surgical treatment always cured the upper airways disorders in patients with chronic nasal obstruction and rhino-sinus inflammation. Improvement of bronchopulmonary disease was reported in about half of the patients (49.4%). Statistically significant results were obtained only in the group with recurrent bronchopulmonary infections (80.9%, p<0.05).
CONCLUSIONS: The study confirms that RBS may be quite frequent in childhood. This disorder has a multifactorial pathogenesis prevalently due to nasal obstruction and rhino-sinus infections. In the population studied, among the lower airways disorders, only infective bronchopulmonary inflammation showed a significant correlation in the assessment between lower and upper airways disorders. In order to prevent the progression of the syndrome to serious pathologic events of the lower airways, a prompt and effective treatment of children's nasal disorders is thus recommended.

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Year:  2005        PMID: 16214227     DOI: 10.1016/j.ijporl.2005.07.019

Source DB:  PubMed          Journal:  Int J Pediatr Otorhinolaryngol        ISSN: 0165-5876            Impact factor:   1.675


  1 in total

1.  Analysis of lower airway inflammation in a rabbit model of acute rhinosinusitis.

Authors:  Adin Selcuk; Ozgur Akdogan; Seren Gulsen Giray; Kursat Murat Ozcan; Ibrahim Ozcan; Huseyin Dere; Serdar Ensari; Candan Ozogul
Journal:  Indian J Otolaryngol Head Neck Surg       Date:  2011-04-11
  1 in total

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