| Literature DB >> 16213209 |
Yuichi J Machida1, Joyce L Hamlin, Anindya Dutta.
Abstract
DNA replication is tightly regulated at the initiation step by both the cell cycle machinery and checkpoint pathways. Here, we discuss recent advances in understanding how replication is initiated in metazoans at the correct chromosome positions, at the appropriate time, and only once per cell cycle.Mesh:
Substances:
Year: 2005 PMID: 16213209 DOI: 10.1016/j.cell.2005.09.019
Source DB: PubMed Journal: Cell ISSN: 0092-8674 Impact factor: 41.582