Literature DB >> 16213121

Antiplasmodial diterpenoid from the leaves of Hyptis suaveolens.

J C Chukwujekwu1, P Smith, P H Coombes, D A Mulholland, J van Staden.   

Abstract

Bioactivity-guided fractionation of the petroleum ether extract of the leaves of Hyptis suaveolens, widely used in Traditional Medicine, has led to the isolation of an abietane-type diterpenoid endoperoxide, 13 alpha-epi-dioxiabiet-8(14)-en-18-ol, displaying high antiplasmodial activity (IC(50) 0.1 microg/ml).

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Year:  2005        PMID: 16213121     DOI: 10.1016/j.jep.2005.08.018

Source DB:  PubMed          Journal:  J Ethnopharmacol        ISSN: 0378-8741            Impact factor:   4.360


  14 in total

1.  Antiplasmodial activity of botanical extracts against Plasmodium falciparum.

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Journal:  Parasitol Res       Date:  2010-11-16       Impact factor: 2.289

Review 2.  Plant-derived antimicrobials to fight against multi-drug-resistant human pathogens.

Authors:  Ramesh Subramani; Mathivanan Narayanasamy; Klaus-D Feussner
Journal:  3 Biotech       Date:  2017-06-29       Impact factor: 2.406

3.  Antimalarial Natural Products.

Authors:  David G I Kingston; Maria Belen Cassera
Journal:  Prog Chem Org Nat Prod       Date:  2022

Review 4.  Therapeutic Potentials of Antiviral Plants Used in Traditional African Medicine With COVID-19 in Focus: A Nigerian Perspective.

Authors:  Alfred Francis Attah; Adeshola Adebayo Fagbemi; Olujide Olubiyi; Hannah Dada-Adegbola; Akinseinde Oluwadotun; Anthony Elujoba; Chinedum Peace Babalola
Journal:  Front Pharmacol       Date:  2021-04-26       Impact factor: 5.810

5.  Production of podophyllotoxin from roots and plantlets of Hyptis suaveolens cultivated in vitro.

Authors:  Rafael A Velóz; Alexandre Cardoso-Taketa; María Luisa Villarreal
Journal:  Pharmacognosy Res       Date:  2013-04

Review 6.  The potential of anti-malarial compounds derived from African medicinal plants, part I: a pharmacological evaluation of alkaloids and terpenoids.

Authors:  Pascal Amoa Onguéné; Fidele Ntie-Kang; Lydia Likowo Lifongo; Jean Claude Ndom; Wolfgang Sippl; Luc Meva'a Mbaze
Journal:  Malar J       Date:  2013-12-13       Impact factor: 2.979

Review 7.  A bioactivity versus ethnobotanical survey of medicinal plants from Nigeria, west Africa.

Authors:  Lydia L Lifongo; Conrad V Simoben; Fidele Ntie-Kang; Smith B Babiaka; Philip N Judson
Journal:  Nat Prod Bioprospect       Date:  2014-03-02

Review 8.  Potential antimalarials from African natural products: A reviw.

Authors:  Bashir Lawal; Oluwatosin Kudirat Shittu; Adamu Yusuf Kabiru; Ali Audu Jigam; Maimuna Bello Umar; Eustace Bonghan Berinyuy; Blessing Uchenna Alozieuwa
Journal:  J Intercult Ethnopharmacol       Date:  2015-10-29

9.  Evaluation of glucose utilization capacity of bioactivity-guided fractions of Barleria prionitis Linn and Hyptis suaveolens (L.) Poit in isolated rat hemidiaphragm.

Authors:  Azmath Unnisa Begum; Sama Venkatesh; Jaya Prakash; Ravi Alvala
Journal:  Ayu       Date:  2016 Apr-Jun

10.  In Vivo Anti-Malarial Activity of Heracleum persicum Fruit Extract, in Combination with Chloroquine against Chloroquine-Sensitive Strain of Plasmodium berghei.

Authors:  Nahideh Mazhari; Mehdi Nateghpour; Peyman Heydarian; Leila Farivar; Effat Souri; Afsaneh Motevalli Haghi
Journal:  Iran J Public Health       Date:  2018-06       Impact factor: 1.429

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