| Literature DB >> 16211336 |
Imad Uthman1, Zahi Touma, Jinane El-Sayyad, Fares Zaitoun.
Abstract
Infusion of the antitumor necrosis factor-alpha chimeric monoclonal antibody infliximab can be associated with the development of severe infusion reactions (IR) during retreatment. We present the case of two rheumatoid arthritis patients with a history of severe acute IR to infliximab who subsequently underwent successful infusion using a prophylactic treatment with a combination of H1 and H2 receptor blockers, hydrocortisone, and diphenhydramine.Entities:
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Year: 2005 PMID: 16211336 DOI: 10.1007/s10067-005-0029-9
Source DB: PubMed Journal: Clin Rheumatol ISSN: 0770-3198 Impact factor: 2.980