Literature DB >> 16210551

Thrombolysis beyond the guidelines: two treatments in one subject within 90 hours based on a modified magnetic resonance imaging brain clock concept.

Raffi Topakian1, Franz Gruber, Franz A Fellner, Hans-Peter Haring, Franz T Aichner.   

Abstract

BACKGROUND AND
PURPOSE: We report the first case of 2 intravenous thrombolysis treatments within 90 hours in a patient with early recurrent stroke. SUMMARY OF REVIEW: A 50-year-old man had improved significantly after intravenous thrombolysis for acute stroke. On the fourth day, he deteriorated dramatically because of recurrent stroke. Evidence of vessel reocclusion and profound perfusion/diffusion mismatch constituted the rationale for a second thrombolysis treatment, which resulted in vessel recanalization and significant neurologic improvement.
CONCLUSIONS: The pathophysiological information obtained by multimodal magnetic resonance imaging may suit as a brain clock when repeat thrombolysis treatment is considered for early recurrent stroke.

Entities:  

Mesh:

Year:  2005        PMID: 16210551     DOI: 10.1161/01.STR.0000185799.22645.8a

Source DB:  PubMed          Journal:  Stroke        ISSN: 0039-2499            Impact factor:   7.914


  5 in total

Review 1.  Absolute and Relative Contraindications to IV rt-PA for Acute Ischemic Stroke.

Authors:  Jennifer E Fugate; Alejandro A Rabinstein
Journal:  Neurohospitalist       Date:  2015-07

2.  Repeated early thrombolysis in cervical spinal cord ischemia.

Authors:  Thorleif Etgen; Constanze Höcherl
Journal:  J Thromb Thrombolysis       Date:  2016-07       Impact factor: 2.300

3.  Repeated thrombolytic therapy in patients with recurrent acute ischemic stroke.

Authors:  Han Soo Yoo; Young Dae Kim; Hye Sun Lee; Dongbeom Song; Tae Jin Song; Byung Moon Kim; Dong Joon Kim; Dong Ik Kim; Ji Hoe Heo; Hyo Suk Nam
Journal:  J Stroke       Date:  2013-09-27       Impact factor: 6.967

4.  Adverse outcome of early recurrent ischemic stroke secondary to atrial fibrillation after repeated systemic thrombolysis.

Authors:  Luciano A Sposato; Valeria Salutto; Diego E Beratti; Paula Monti; Patricia M Riccio; Claudio Mazia
Journal:  Case Rep Vasc Med       Date:  2013-08-06

Review 5.  Why not Intravenous Thrombolysis in Patients with Recurrent Stroke within 3 Months?

Authors:  Chuanjie Wu; Di Wu; Jian Chen; Chuanhui Li; Xunming Ji
Journal:  Aging Dis       Date:  2018-04-01       Impact factor: 6.745

  5 in total

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