Literature DB >> 16209644

Online coupling of capillary electrophoresis with mass spectrometry for the identification of biomarkers for clinical diagnosis.

Eva M Weissinger1, Bernd Hertenstein, Harald Mischak, Arnold Ganser.   

Abstract

Proteomic screening of complex biologic samples is of increasing importance in clinical research and diagnosis. In the postgenomic area it is evident that changes of the composition of body fluids, as well as post-translational modifications of proteins and peptides, provide more information than genetic typing. The study of these changes allows the state of health or disease of particular organs, and consequently, the whole organism, to be described. This review describes the application of capillary electrophoresis coupled online to an electrospray ionization time-of-flight mass spectrometer to the analysis of body fluids obtained from patients for the identification of biomarkers for diagnostic purposes.

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Year:  2005        PMID： 16209644     DOI： 10.1586/14789450.2.5.639

Source DB:  PubMed          Journal:  Expert Rev Proteomics        ISSN： 1478-9450            Impact factor:   3.940


  7 in total

Review 1.  Modern instrumental methods in forensic toxicology.

Authors:  Michael L Smith; Shawn P Vorce; Justin M Holler; Eric Shimomura; Joe Magluilo; Aaron J Jacobs; Marilyn A Huestis
Journal:  J Anal Toxicol       Date:  2007-06       Impact factor: 3.367

2.  High-resolution proteome/peptidome analysis of peptides and low-molecular-weight proteins in urine.

Authors:  Harald Mischak; Bruce A Julian; Jan Novak
Journal:  Proteomics Clin Appl       Date:  2007-07-10       Impact factor: 3.494

3.  A tool for biomarker discovery in the urinary proteome: a manually curated human and animal urine protein biomarker database.

Authors:  Chen Shao; Menglin Li; Xundou Li; Lilong Wei; Lisi Zhu; Fan Yang; Lulu Jia; Yi Mu; Jiangning Wang; Zhengguang Guo; Dan Zhang; Jianrui Yin; Zhigang Wang; Wei Sun; Zhengguo Zhang; Youhe Gao
Journal:  Mol Cell Proteomics       Date:  2011-08-29       Impact factor: 5.911

4.  CE-MS analysis of the human urinary proteome for biomarker discovery and disease diagnostics.

Authors:  Joshua J Coon; Petra Zürbig; Mohammed Dakna; Anna F Dominiczak; Stéphane Decramer; Danilo Fliser; Moritz Frommberger; Igor Golovko; David M Good; Stefan Herget-Rosenthal; Joachim Jankowski; Bruce A Julian; Markus Kellmann; Walter Kolch; Ziad Massy; Jan Novak; Kasper Rossing; Joost P Schanstra; Eric Schiffer; Dan Theodorescu; Raymond Vanholder; Eva M Weissinger; Harald Mischak; Philippe Schmitt-Kopplin
Journal:  Proteomics Clin Appl       Date:  2008-07-10       Impact factor: 3.494

Review 5.  Capillary electrophoresis-mass spectrometry as a powerful tool in biomarker discovery and clinical diagnosis: an update of recent developments.

Authors:  Harald Mischak; Joshua J Coon; Jan Novak; Eva M Weissinger; Joost P Schanstra; Anna F Dominiczak
Journal:  Mass Spectrom Rev       Date:  2009 Sep-Oct       Impact factor: 10.946

Review 6.  B-Cell-Based and Soluble Biomarkers in Body Liquids for Predicting Acute/Chronic Graft-versus-Host Disease after Allogeneic Hematopoietic Stem Cell Transplantation.

Authors:  Mateja Kralj Juric; Maxim Shevtsov; Petra Mozes; Justyna Ogonek; Rachel E Crossland; Anne M Dickinson; Hildegard T Greinix; Ernst Holler; Eva M Weissinger; Gabriele Multhoff
Journal:  Front Immunol       Date:  2017-01-16       Impact factor: 7.561

Review 7.  Sample preparation for serum/plasma profiling and biomarker identification by mass spectrometry.

Authors:  Jose L Luque-Garcia; Thomas A Neubert
Journal:  J Chromatogr A       Date:  2006-12-12       Impact factor: 4.759
  7 in total

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