Literature DB >> 16209583

Multicomponent synthesis of spiroisoxazolines.

Mauro F A Adamo1, Donato Donati, Eleanor F Duffy, Piero Sarti-Fantoni.   

Abstract

A three-component one-pot procedure (3-MCR) was developed to assemble the spiroisoxazoline nucleus from commercially available materials. This new methodology affords the title compounds in high yields and without the use of chromatography.

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Year:  2005        PMID： 16209583     DOI： 10.1021/jo051181w

Source DB:  PubMed          Journal:  J Org Chem        ISSN： 0022-3263            Impact factor:   4.354


  6 in total

1.  One Pot Spiropyrazoline Synthesis via Intramolecular Cyclization/Methylation.

Authors:  Sureshbabu Dadiboyena; Ashton T Hamme
Journal:  Tetrahedron Lett       Date:  2011-05-18       Impact factor: 2.415

2.  Solid Phase Synthesis of Isoxazole and Isoxazoline-carboxamides via [2+3]-Dipolar Cycloaddition Using Resin-bound Alkynes or Alkenes.

Authors:  Sureshbabu Dadiboyena; Adel Nefzi
Journal:  Tetrahedron Lett       Date:  2012-04-18       Impact factor: 2.415

3.  Construction of Novel Spiroisoxazolines via Intramolecular Cyclization/Methylation.

Authors:  Erick D Ellis; Jianping Xu; Edward J Valente; Ashton T Hamme
Journal:  Tetrahedron Lett       Date:  2009-09-30       Impact factor: 2.415

4.  Synthesis and Tautomerism of Spiro-Pyrazolines.

Authors:  Sureshbabu Dadiboyena; Edward J Valente; Ashton T Hamme
Journal:  Tetrahedron Lett       Date:  2014-04-02       Impact factor: 2.415

5.  Diastereoselective additive trifluoromethylation/halogenation of isoxazole triflones: synthesis of all-carbon-functionalized trifluoromethyl isoxazoline triflones.

Authors:  Hiroyuki Kawai; Yutaka Sugita; Etsuko Tokunaga; Hiroyasu Sato; Motoo Shiro; Norio Shibata
Journal:  ChemistryOpen       Date:  2014-02-13       Impact factor: 2.911

6.  Vinylogous Nitro-Haloform Reaction Enables Aromatic Amination.

Authors:  Claudio Monasterolo; Mauro F A Adamo
Journal:  Org Lett       Date:  2022-06-28       Impact factor: 6.072
  6 in total

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