Literature DB >> 16209530

Convenient access to glutamic acid side chain homologues compatible with solid phase peptide synthesis.

Shannon J Ryan1, Yongda Zhang, Alan J Kennan.   

Abstract

[reaction: see text] Preparation of several side chain length variants of glutamic acid is achieved via olefin cross metathesis of allyl glycine derivatives. The products are suitably protected for direct use in Fmoc solid-phase peptide synthesis, as demonstrated by successful synthesis of test sequences.

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Year:  2005        PMID: 16209530     DOI: 10.1021/ol0520222

Source DB:  PubMed          Journal:  Org Lett        ISSN: 1523-7052            Impact factor:   6.005


  5 in total

1.  Strategies for recognition of stem-loop RNA structures by synthetic ligands: application to the HIV-1 frameshift stimulatory sequence.

Authors:  Prakash B Palde; Leslie O Ofori; Peter C Gareiss; Jaclyn Lerea; Benjamin L Miller
Journal:  J Med Chem       Date:  2010-08-26       Impact factor: 7.446

2.  Synthesis of a Homologous Series of Side Chain Extended Orthogonally-Protected Aminooxy-Containing Amino Acids.

Authors:  Fa Liu; Joshua Thomas; Terrence R Burke
Journal:  Synthesis (Stuttg)       Date:  2008       Impact factor: 3.157

3.  Ester Formation via Symbiotic Activation Utilizing Trichloroacetimidate Electrophiles.

Authors:  Nivedita S Mahajani; Rowan I L Meador; Tomas J Smith; Sarah E Canarelli; Arijit A Adhikari; Jigisha P Shah; Christopher M Russo; Daniel R Wallach; Kyle T Howard; Alexandra M Millimaci; John D Chisholm
Journal:  J Org Chem       Date:  2019-05-30       Impact factor: 4.354

4.  Asymmetric Petasis Borono-Mannich Allylation Reactions Catalyzed by Chiral Biphenols.

Authors:  Yao Jiang; Scott E Schaus
Journal:  Angew Chem Int Ed Engl       Date:  2017-01-04       Impact factor: 15.336

5.  In situ monitoring of backbone thioester exchange by 19F NMR.

Authors:  William C Pomerantz; Erik B Hadley; Charles G Fry; Samuel H Gellman
Journal:  Chembiochem       Date:  2009-09-04       Impact factor: 3.164

  5 in total

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