| Literature DB >> 16209481 |
Carlos Alemparte1, Gonzalo Blay, Karl Anker Jørgensen.
Abstract
[reaction: see text] Silver fluoride and cinchona alkaloids catalyze the diastereo- and enantioselective 1,3-dipolar cycloaddition between azomethine ylides, generated from N-alkylideneglycine esters, and acrylates to give the corresponding endo-adducts. Azomethine ylides derived from aromatic and aliphatic aldehydes react in a highly diastereoselective reaction with good yields and enantioselectivities of the substituted pyrrolidines.Entities:
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Year: 2005 PMID： 16209481 DOI： 10.1021/ol0514653
Source DB: PubMed Journal: Org Lett ISSN： 1523-7052 Impact factor: 6.005