Literature DB >> 16209479

New conjunctive reagents as cross-coupling partners en route to retinoid-like polyenes.

Bruce H Lipshutz1, Giuliano C Clososki, Will Chrisman, David W Chung, David B Ball, Jennifer Howell.   

Abstract

[structure: see text] New conjunctive reagents E-2 and Z-3 can be used, after transmetalation, in Negishi couplings with vinyl and aryl iodides. The subsequently unmasked terminal alkynes can be further manipulated to arrive at retinoid-like products.

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Year:  2005        PMID： 16209479     DOI： 10.1021/ol051406p

Source DB:  PubMed          Journal:  Org Lett        ISSN： 1523-7052            Impact factor:   6.005


  4 in total

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Authors:  Suk Joong Lee; Kaitlyn C Gray; James S Paek; Martin D Burke
Journal:  J Am Chem Soc       Date:  2008-01-16       Impact factor: 15.419

2.  Total synthesis of the Hsp90 inhibitor geldanamycin.

Authors:  Hua-Li Qin; James S Panek
Journal:  Org Lett       Date:  2008-05-20       Impact factor: 6.005

3.  Seebach's conjunctive reagent enables double cyclizations.

Authors:  Brent D Chandler; Jason T Roland; Yukai Li; Erik J Sorensen
Journal:  Org Lett       Date:  2010-06-18       Impact factor: 6.005

4.  Insights into the structure-activity relationship of the anticancer compound ZJ-101, a derivative of marine natural product superstolide A: A critical role played by the conjugated trienyl lactone moiety.

Authors:  Shan Qian; Aashay K Shah; Sarah A Head; Jun O Liu; Zhendong Jin
Journal:  Bioorg Med Chem Lett       Date:  2016-06-22       Impact factor: 2.823
  4 in total

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