Pulmonary nodular opacities after transbronchial biopsy in patients with lung transplants.

Focal nodular opacities were seen on 26 of 74 (35%) postbiopsy radiographs obtained in 39 patients who underwent lung transplantation. The subsequent clinical course and diagnostic evaluation suggested that the opacities were due to focal hemorrhage at the biopsy sites. This finding was evident on only three of 40 (8%) postbiopsy radiographs obtained in 40 control patients who underwent transbronchial biopsy for diffuse interstitial lung disease. The differential diagnosis of new pulmonary nodular opacities in lung transplantation patients should include focal postbiopsy hematomas, because of their relatively frequent occurrence in this clinical situation.