Literature DB >> 16206342

Demographic and clinical factors associated with in-hospital death among patients with systemic sclerosis.

Paul J Nietert1, Richard M Silver, Holly C Mitchell, Stephanie R Shaftman, Barbara C Tilley.   

Abstract

OBJECTIVE: To examine demographic and clinical predictors of in-hospital death of patients with systemic sclerosis (SSc) and determine to what extent apparent racial differences may be attributed to socioeconomic factors.
METHODS: Data were obtained on all hospitalizations in South Carolina for patients who were ever hospitalized between 1996 and 2000 with a diagnosis of SSc. Multiple logistic regression was used to examine predictors of in-hospital death among whites, blacks, and other patients.
RESULTS: Proportions of in-hospital deaths among blacks (23.0%) and others (27.7%) were higher than among whites (15.6%), a finding that remained after adjustment for other sociodemographic and clinical factors (black/white odds ratio: 1.70, 95% confidence interval: 1.01-2.86; other/white OR 2.06, 95% CI 1.04-4.09). Other factors associated with in-hospital death included transfer status, emergency admission, length of stay, number of hospitalizations during the time period, and presence of congestive heart failure (OR 1.79; 95% CI 1.06-3.03) or hypertension (OR 0.41; 95% CI 0.23-0.71).
CONCLUSION: Black and other non-white patients with SSc appear to experience an elevated risk of death during their hospital stays. Further research is necessary to understand the reasons for these disparities.

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Mesh:

Year:  2005        PMID: 16206342

Source DB:  PubMed          Journal:  J Rheumatol        ISSN: 0315-162X            Impact factor:   4.666


  10 in total

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Journal:  Semin Arthritis Rheum       Date:  2011-03-22       Impact factor: 5.532

2.  Predictors of inpatient mortality in patients with systemic sclerosis: a case control study.

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3.  Acute hospitalization in a cohort of patients with systemic sclerosis: a 10-year retrospective cohort study.

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4.  Ethnic disparities among patients with systemic lupus erythematosus in South Carolina.

Authors:  Erica Anderson; Paul J Nietert; Diane L Kamen; Gary S Gilkeson
Journal:  J Rheumatol       Date:  2008-03-15       Impact factor: 4.666

5.  Predictors of interstitial lung disease in early systemic sclerosis: a prospective longitudinal study of the GENISOS cohort.

Authors:  Shervin Assassi; Roozbeh Sharif; Robert E Lasky; Terry A McNearney; Rosa M Estrada-Y-Martin; Hilda Draeger; Deepthi K Nair; Marvin J Fritzler; John D Reveille; Frank C Arnett; Maureen D Mayes
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6.  Caveolin-1 deficiency may predispose African Americans to systemic sclerosis-related interstitial lung disease.

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Review 8.  Racial differences between blacks and whites with systemic sclerosis.

Authors:  Richard M Silver; Galina Bogatkevich; Elena Tourkina; Paul J Nietert; Stanley Hoffman
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10.  D1398G Variant of MET Is Associated with Impaired Signaling of Hepatocyte Growth Factor in Alveolar Epithelial Cells and Lung Fibroblasts.

Authors:  Ilia Atanelishvili; Yuichiro Shirai; Tanjina Akter; Atsushi Noguchi; Kurt T Ash; Suniti Misra; Sibnath Ghatak; Richard M Silver; Galina S Bogatkevich
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  10 in total

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