Literature DB >> 16206045

A silychristin isomer and variation of flavonolignan levels in milk thistle (Silybum marianum) fruits.

Wendy A Smith1, Denis R Lauren, Elaine J Burgess, Nigel B Perry, Richard J Martin.   

Abstract

A new natural product has been isolated from silymarin, the hepatoprotective extract of milk thistle (Silybum marianum) fruits. This was shown by NMR spectroscopy to be silychristin B (8), a diastereoisomer of the known silychristin (7). Levels of these and the other flavonolignans varied markedly in fruits of different S. marianum samples.

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Year:  2005        PMID： 16206045     DOI： 10.1055/s-2005-864187

Source DB:  PubMed          Journal:  Planta Med        ISSN： 0032-0943            Impact factor:   3.352


  3 in total

1.  Silybum marianum pericarp yields enhanced silymarin products.

Authors:  Sameh F AbouZid; Shao-Nong Chen; James B McAlpine; J Brent Friesen; Guido F Pauli
Journal:  Fitoterapia       Date:  2016-05-24       Impact factor: 2.882

2.  Regioselective alcoholysis of silychristin acetates catalyzed by lipases.

Authors:  Eva Vavříková; Paolo Gavezzotti; Kateřina Purchartová; Kateřina Fuksová; David Biedermann; Marek Kuzma; Sergio Riva; Vladimír Křen
Journal:  Int J Mol Sci       Date:  2015-05-26       Impact factor: 5.923

3.  Discovery of Potent Glucokinase and PPARγ Dual-Target Agonists through an Innovative Scheme for Regioselective Modification of Silybin.

Authors:  Zhipeng Zhang; Yanqiu Meng; Zhan Wang; Yu Mei; Shite Gao; Yuejiao Wu; Shuxian Du
Journal:  ACS Omega       Date:  2022-01-20
  3 in total

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