Literature DB >> 16205862

Thrombolysis in young adults.

Jeffrey C Wagner1, Helmi L Lutsep.   

Abstract

Obstacles to thrombolytic treatment could be unique in young stroke patients and identifying and addressing them would potentially enhance outcomes. However, it has not been well studied how age affects the time to presentation, diagnosis or treatment of acute strokes. Although studies suggest that younger patients may be more aware of stroke symptoms and signs than older ones, they may be less likely to use emergency medical services. Importantly, for strokes of similar severity, younger patients have more favorable outcomes with thrombolysis than older patients. On the other hand, young patients who experience extensive middle cerebral artery strokes are more likely to develop fatal brain edema than older patients. Current data support the use of thrombolytics for all ischemic stroke etiologies, including entities such as cervical artery dissection that are more common in young patients.

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Year:  2005        PMID: 16205862     DOI: 10.1007/s11239-005-3207-3

Source DB:  PubMed          Journal:  J Thromb Thrombolysis        ISSN: 0929-5305            Impact factor:   2.300


  25 in total

1.  Intra-arterial prourokinase for acute ischemic stroke. The PROACT II study: a randomized controlled trial. Prolyse in Acute Cerebral Thromboembolism.

Authors:  A Furlan; R Higashida; L Wechsler; M Gent; H Rowley; C Kase; M Pessin; A Ahuja; F Callahan; W M Clark; F Silver; F Rivera
Journal:  JAMA       Date:  1999-12-01       Impact factor: 56.272

2.  Intravenous tPA in acute ischemic stroke related to internal carotid artery dissection.

Authors:  L Derex; N Nighoghossian; F Turjman; M Hermier; J Honnorat; P Neuschwander; J C Froment; P Trouillas
Journal:  Neurology       Date:  2000-06-13       Impact factor: 9.910

3.  Early hemicraniectomy in patients with complete middle cerebral artery infarction.

Authors:  S Schwab; T Steiner; A Aschoff; S Schwarz; H H Steiner; O Jansen; W Hacke
Journal:  Stroke       Date:  1998-09       Impact factor: 7.914

4.  Prehospital and emergency department delays after acute stroke: the Genentech Stroke Presentation Survey.

Authors:  D L Morris; W Rosamond; K Madden; C Schultz; S Hamilton
Journal:  Stroke       Date:  2000-11       Impact factor: 7.914

5.  Tissue plasminogen activator for acute ischemic stroke.

Authors: 
Journal:  N Engl J Med       Date:  1995-12-14       Impact factor: 91.245

6.  Treatment of right hemispheric cerebral infarction by hemicraniectomy.

Authors:  J B Delashaw; W C Broaddus; N F Kassell; E C Haley; G A Pendleton; D G Vollmer; W W Maggio; M S Grady
Journal:  Stroke       Date:  1990-06       Impact factor: 7.914

7.  Generalized efficacy of t-PA for acute stroke. Subgroup analysis of the NINDS t-PA Stroke Trial.

Authors: 
Journal:  Stroke       Date:  1997-11       Impact factor: 7.914

8.  Cerebral infarction in young people. A study of 148 patients with early cerebral angiography.

Authors:  F Lisovoski; P Rousseaux
Journal:  J Neurol Neurosurg Psychiatry       Date:  1991-07       Impact factor: 10.154

9.  A population-based study of acute stroke and TIA diagnosis.

Authors:  L B Morgenstern; L D Lisabeth; A C Mecozzi; M A Smith; P J Longwell; D A McFarling; J M H Risser
Journal:  Neurology       Date:  2004-03-23       Impact factor: 9.910

10.  Factors delaying hospital admission after acute stroke.

Authors:  R Fogelholm; K Murros; A Rissanen; M Ilmavirta
Journal:  Stroke       Date:  1996-03       Impact factor: 7.914

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  5 in total

Review 1.  Ischemic stroke in the elderly: an overview of evidence.

Authors:  Ruo-Li Chen; Joyce S Balami; Margaret M Esiri; Liang-Kung Chen; Alastair M Buchan
Journal:  Nat Rev Neurol       Date:  2010-04-06       Impact factor: 42.937

2.  Changes in experimental stroke outcome across the life span.

Authors:  Fudong Liu; Rongwen Yuan; Sharon E Benashski; Louise D McCullough
Journal:  J Cereb Blood Flow Metab       Date:  2009-02-18       Impact factor: 6.200

3.  Intravenous thrombolysis in stroke patients under 55 years of age: is there a different effect according to etiology and severity?

Authors:  Daniel Prefasi; Blanca Fuentes; Patricia Martínez-Sánchez; Ana Rodríguez-Sanz; Gerardo Ruiz-Ares; Borja Sanz-Cuesta; Manuel Lara Lara; Exuperio Díez-Tejedor
Journal:  J Thromb Thrombolysis       Date:  2014-05       Impact factor: 2.300

4.  Stroke care in young patients.

Authors:  L Tancredi; F Martinelli Boneschi; M Braga; I Santilli; C Scaccabarozzi; P Lattuada; M Sessa; L Fumagalli; S Iurlaro; I Neromante; M L De Lodovici; D V Roccatagliata; G Giacalone; M Arnaboldi; V Crespi; E Agostoni; G C Comi; C Ferrarese; R Sterzi
Journal:  Stroke Res Treat       Date:  2013-02-26

5.  Critical role of sphingosine-1-phosphate receptor-2 in the disruption of cerebrovascular integrity in experimental stroke.

Authors:  Gab Seok Kim; Li Yang; Guoqi Zhang; Honggang Zhao; Magdy Selim; Louise D McCullough; Michael J Kluk; Teresa Sanchez
Journal:  Nat Commun       Date:  2015-08-05       Impact factor: 14.919

  5 in total

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