| Literature DB >> 16203155 |
Francesco Peri1, Chiara Marinzi, Marek Barath, Francesca Granucci, Matteo Urbano, Francesco Nicotra.
Abstract
A mimetic of Lipid A with a beta-N(OMe) glycosidic linkage, four linear C-14 hydrophobic chains and without phosphate groups has been prepared together with its beta-O-linked analogue. Both these molecules were active in inhibiting the inflammatory action of Escherichia coli lipid A on MT2 macrophages in a dose-dependent manner, while they were completely devoid of inflammatory activity.Entities:
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Year: 2005 PMID： 16203155 DOI： 10.1016/j.bmc.2005.08.047
Source DB: PubMed Journal: Bioorg Med Chem ISSN： 0968-0896 Impact factor: 3.641