OBJECTIVE: This study was undertaken to prospectively evaluate the effect of early stage endometrial cancer, age, and obesity on quality of life (QOL). STUDY DESIGN: Women undergoing surgery for endometrial cancer or an adnexal mass determined at surgery to be benign (controls) were enrolled preoperatively and followed for 6 months. RESULTS: Seventy-nine women completed the study. Functional Assessment of Cancer Therapy (FACT-G) scores increased significantly in all women; however, significant differences by patient weight and age were obtained. Obesity was associated with decreased physical FACT-G and SF-36 scores. Older women had lower SF-36 physical scores, higher emotional scores, and less change over time. CONCLUSION: Women with early endometrial cancer had similar changes in QOL as those who received surgery for benign disease. Obese and elderly women had domain alterations. Given the aging population and rising incidence of obesity, these results emphasize the need for QOL interventions in postoperative gynecologic care of these patients.
OBJECTIVE: This study was undertaken to prospectively evaluate the effect of early stage endometrial cancer, age, and obesity on quality of life (QOL). STUDY DESIGN:Women undergoing surgery for endometrial cancer or an adnexal mass determined at surgery to be benign (controls) were enrolled preoperatively and followed for 6 months. RESULTS: Seventy-nine women completed the study. Functional Assessment of Cancer Therapy (FACT-G) scores increased significantly in all women; however, significant differences by patient weight and age were obtained. Obesity was associated with decreased physical FACT-G and SF-36 scores. Older women had lower SF-36 physical scores, higher emotional scores, and less change over time. CONCLUSION:Women with early endometrial cancer had similar changes in QOL as those who received surgery for benign disease. Obese and elderly women had domain alterations. Given the aging population and rising incidence of obesity, these results emphasize the need for QOL interventions in postoperative gynecologic care of these patients.
Authors: K Basen-Engquist; C Carmack; J Brown; A Jhingran; G Baum; J Song; S Scruggs; M C Swartz; M G Cox; K H Lu Journal: Gynecol Oncol Date: 2014-04 Impact factor: 5.482
Authors: Amerigo Rossi; Carol Ewing Garber; Gurpreet Kaur; Xiaonan Xue; Gary L Goldberg; Nicole S Nevadunsky Journal: Support Care Cancer Date: 2017-02-16 Impact factor: 3.603
Authors: Kemi M Doll; Alison K Kalinowski; Anna C Snavely; Debra E Irwin; Jeannette T Bensen; Victoria L Bae-Jump; Kenneth H Kim; Linda Van Le; Daniel L Clarke-Pearson; Paola A Gehrig Journal: Cancer Date: 2014-09-23 Impact factor: 6.860
Authors: David A Iglesias; Shannon N Westin; Vijayashri Rallapalli; Marilyn Huang; Bryan Fellman; Diana Urbauer; Michael Frumovitz; Pedro T Ramirez; Pamela T Soliman Journal: Gynecol Oncol Date: 2012-01-16 Impact factor: 5.482
Authors: Lucas Minig; Jorge Iván Vélez; Edward L Trimble; Roberto Biffi; Angelo Maggioni; Diana D Jeffery Journal: Support Care Cancer Date: 2012-08-29 Impact factor: 3.603
Authors: Sean M Hammer; Justin C Brown; Saya Segal; Christina S Chu; Kathryn H Schmitz Journal: Med Sci Sports Exerc Date: 2014-12 Impact factor: 5.411
Authors: Weiya Z Wysham; Dario R Roque; Jianjun Han; Lu Zhang; Hui Guo; Paola A Gehrig; Chunxiao Zhou; Victoria L Bae-Jump Journal: Target Oncol Date: 2016-12 Impact factor: 4.493
Authors: Leigh A Cantrell; Chunxiao Zhou; Alberto Mendivil; Kimberly M Malloy; Paola A Gehrig; Victoria L Bae-Jump Journal: Gynecol Oncol Date: 2009-10-12 Impact factor: 5.482