| Literature DB >> 16201775 |
Ryo Takita1, Kenichiro Yakura, Takashi Ohshima, Masakatsu Shibasaki.
Abstract
Asymmetric alkynylation of both aromatic and aliphatic aldehydes using catalytic amounts of In(III)/BINOL is described. Dual activation of both substrates due to the "bifunctional character" of the indium(III) catalyst enables a broad range of substrate generality with high enantioselectivity (83 to >99% ee).Entities:
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Year: 2005 PMID： 16201775 DOI： 10.1021/ja053946n
Source DB: PubMed Journal: J Am Chem Soc ISSN： 0002-7863 Impact factor: 15.419