Literature DB >> 16201332

[Morpho-functional characteristic of dog spinal ganglion neurons in post-distraction period].

G D Safonova, A P Kovalenko.   

Abstract

The object of this work was to study the morpho-functional state of spinal ganglion neurons and to conduct the comparative quantitative analysis of the changes of neuronglial relations after hindlimb elongation in mongrel dogs by 14-16% of its initial length using different elongation rates. The longitudinal 5 microm thick serial sections of L(VI), L(VII) and S(I) ganglia stained with Nissl's thionine and cresyl violet and Einarssons's gallocyanin-chrome alume were studied. By days 45-48 of an experiment the reversible changes in the structure of some part of neurons were demonstrated, which included cytoplasmic and nuclear hyperchromatism, peripheral chromatolysis, nuclear and nucleolar dislocation, increase in the number of peri- and interneuronal gliocytes. The changes were most marked in the ganglia ipsilateral to the lengthening side with distraction rate of 3 mm per day; they were minimal contralaterally with the lengthening rate of 1 mm per day.

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Year:  2005        PMID: 16201332

Source DB:  PubMed          Journal:  Morfologiia        ISSN: 1026-3543


  1 in total

1.  Developmental axon stretch stimulates neuron growth while maintaining normal electrical activity, intracellular calcium flux, and somatic morphology.

Authors:  Joseph R Loverde; Bryan J Pfister
Journal:  Front Cell Neurosci       Date:  2015-08-24       Impact factor: 5.505

  1 in total

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