OBJECTIVE: To study the impact of postoperative radiotherapy (RT) on titanium plate mandibular reconstruction. METHODS: Between 1997 and 2002, 66 patients with oral cavity cancers had immediate titanium plate mandibular reconstruction. Thirty-four patients (51.5%) received postoperative RT and 32 patients were treated with surgery alone. Follow-up ranged from 12 to 58 months (median, 24 months). RESULTS: Sixteen of 66 patients (24.2%) had major complications. Ten of 34 patients (29.4%) who received RT had complications compared with 6 of 32 patients (18.8%) after surgery alone (P = 0.312). The plate was removed in 11 patients (16.7%). The success rate of titanium plate reconstruction was 27 of 34 patients (79.4%) who received RT and 28 of 32 patients (87.5%) after surgery alone (P = 0.378). CONCLUSION: The addition of postoperative RT did not increase the risk of complications or the likelihood of successful titanium plate reconstruction.
OBJECTIVE: To study the impact of postoperative radiotherapy (RT) on titanium plate mandibular reconstruction. METHODS: Between 1997 and 2002, 66 patients with oral cavity cancers had immediate titanium plate mandibular reconstruction. Thirty-four patients (51.5%) received postoperative RT and 32 patients were treated with surgery alone. Follow-up ranged from 12 to 58 months (median, 24 months). RESULTS: Sixteen of 66 patients (24.2%) had major complications. Ten of 34 patients (29.4%) who received RT had complications compared with 6 of 32 patients (18.8%) after surgery alone (P = 0.312). The plate was removed in 11 patients (16.7%). The success rate of titanium plate reconstruction was 27 of 34 patients (79.4%) who received RT and 28 of 32 patients (87.5%) after surgery alone (P = 0.378). CONCLUSION: The addition of postoperative RT did not increase the risk of complications or the likelihood of successful titanium plate reconstruction.
Authors: William M Mendenhall; Russell W Hinerman; Robert J Amdur; Robert S Malyapa; Christopher D Lansford; John W Werning; Douglas B Villaret Journal: Clin Med Res Date: 2006-09
Authors: William M Mendenhall; Adam L Holtzman; Roi Dagan; Curtis M Bryant; Kathryn E Hitchcock; Robert J Amdur; Rui P Fernandes Journal: Craniomaxillofac Trauma Reconstr Date: 2020-11-03