Literature DB >> 1619965

The discovery of DuP 753, a potent, orally active nonpeptide angiotensin II receptor antagonist.

J V Duncia1, D J Carini, A T Chiu, A L Johnson, W A Price, P C Wong, R R Wexler, P B Timmermans.   

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Year:  1992        PMID: 1619965     DOI: 10.1002/med.2610120203

Source DB:  PubMed          Journal:  Med Res Rev        ISSN: 0198-6325            Impact factor:   12.944


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  9 in total

1.  Inhibition of angiotensin II-induced inositol phosphate production by triacid nonpeptide antagonists in CHO cells expressing human AT1 receptors.

Authors:  P M Vanderheyden; I Verheijen; F L Fierens; J P DeBacker; G Vauquelin
Journal:  Pharm Res       Date:  2000-12       Impact factor: 4.200

2.  Derivation of a 3D pharmacophore model for the angiotensin-II site one receptor.

Authors:  K Prendergast; K Adams; W J Greenlee; R B Nachbar; A A Patchett; D J Underwood
Journal:  J Comput Aided Mol Des       Date:  1994-10       Impact factor: 3.686

3.  Functional interaction between losartan and central tachykinin NK3 receptors in the conscious rat.

Authors:  P Picard; L Chrétien; R Couture
Journal:  Br J Pharmacol       Date:  1995-04       Impact factor: 8.739

4.  Detecting low-abundance vasoactive peptides in plasma: progress toward absolute quantitation using nano liquid chromatography-mass spectrometry.

Authors:  Mark Lortie; Steven Bark; Roland Blantz; Vivian Hook
Journal:  Anal Biochem       Date:  2009-07-16       Impact factor: 3.365

5.  Prevention by blockade of angiotensin subtype1-receptors of the development of genetic hypertension but not its heritability.

Authors:  P Madeddu; V Anania; M V Varoni; P P Parpaglia; M P Demontis; M C Fattaccio; D Palomba; D Pollock; N Glorioso
Journal:  Br J Pharmacol       Date:  1995-06       Impact factor: 8.739

6.  α-Amino Acid-Isosteric α-Amino Tetrazoles.

Authors:  Ting Zhao; Katarzyna Kurpiewska; Justyna Kalinowska-Tłuścik; Eberhardt Herdtweck; Alexander Dömling
Journal:  Chemistry       Date:  2016-01-28       Impact factor: 5.236

Review 7.  Losartan chemistry and its effects via AT1 mechanisms in the kidney.

Authors:  Feichao Xu; Caiping Mao; Yujuan Liu; Lei Wu; Zhice Xu; Lubo Zhang
Journal:  Curr Med Chem       Date:  2009       Impact factor: 4.530

Review 8.  Novel Cardiac Intracrine Mechanisms Based on Ang-(1-12)/Chymase Axis Require a Revision of Therapeutic Approaches in Human Heart Disease.

Authors:  Santiago Reyes; Jasmina Varagic; Sarfaraz Ahmad; Jessica VonCannon; Neal D Kon; Hao Wang; Leanne Groban; Che Ping Cheng; Louis J Dell'Italia; Carlos M Ferrario
Journal:  Curr Hypertens Rep       Date:  2017-02       Impact factor: 5.369

Review 9.  Rational Design and Synthesis of AT1R Antagonists.

Authors:  Nikitas Georgiou; Vasileios K Gkalpinos; Spyridon D Katsakos; Stamatia Vassiliou; Andreas G Tzakos; Thomas Mavromoustakos
Journal:  Molecules       Date:  2021-05-14       Impact factor: 4.411

  9 in total

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