| Literature DB >> 16198156 |
Karen M Lee1, Matthew J O'Connell.
Abstract
SUMO is a small ubiquitin-like protein that is attached to target proteins, altering their localization and function. The condensin and cohesin-related Smc5/6 complex has been linked to DNA repair and checkpoint responses, but details of its molecular function have remained obscure. Recent reports show one subunit of the complex is a SUMO ligase, providing another link between protein sumoylation and DNA damage responses.Mesh:
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Year: 2005 PMID: 16198156 DOI: 10.1016/j.dnarep.2005.08.003
Source DB: PubMed Journal: DNA Repair (Amst) ISSN: 1568-7856