Literature DB >> 1619698

[Histochemical study of estrogen and progesterone receptors in cervical carcinoma].

H X An1, L Zhang, G R Cai.   

Abstract

Estrogen and progesterone receptors were determined in 56 cases of primary cervical carcinoma tissue by histochemical methods. 42.86% of the 56 cases were ER positive and 46.43% PR positive. No correlation was found between ER and PR status and age, menopausal status of the patient and clinical stage. Adenocarcinoma had significantly higher ER and PR positive rate than squamous carcinoma. Highly differentiated carcinoma had higher ER and PR positive rate than middle- and dedifferentiated carcinoma. A positive correlation between ER and PR and cellular infiltration of stroma and peritumoral reaction of fibrin was found. The patients with ER and PR positive had a significantly higher 5-year survival. ER and PR may be used as prognostic factors in cervical carcinoma.

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Year:  1992        PMID: 1619698     DOI: 10.1007/bf02887761

Source DB:  PubMed          Journal:  J Tongji Med Univ        ISSN: 0257-716X


  9 in total

1.  Cytosolic estrogen and progesterone receptors as prognostic parameters in stage IB cervical carcinoma.

Authors:  L B Twiggs; R A Potish; B S Leung; L F Carson; L L Adcock; J E Savage; K A Prem
Journal:  Gynecol Oncol       Date:  1987-10       Impact factor: 5.482

2.  Cytoplasmic estrogen and progesterone receptors in primary cervical carcinoma: clinical and histopathologic correlates.

Authors:  Y L Gao; L B Twiggs; B S Leung; W C Yu; R A Potish; T Okagaki; L L Adcock; K A Prem
Journal:  Am J Obstet Gynecol       Date:  1983-06-01       Impact factor: 8.661

3.  The histopathological evaluation of human breast cancers in correlation with estrogen receptor values.

Authors:  F F Parl; R K Wagner
Journal:  Cancer       Date:  1980-07-15       Impact factor: 6.860

4.  Estrogen and progesterone receptor sites in malignancies of the uterine cervix, vagina, and vulva.

Authors:  L C Ford; J S Berek; L D Lagasse; N F Hacker; Y L Heins; R J DeLange
Journal:  Gynecol Oncol       Date:  1983-02       Impact factor: 5.482

5.  The autoradiographic demonstration of estrogen binding in normal human cervix and vagina during the menstrual cycle, pregnancy, and the menopause.

Authors:  S F Gould; J M Shannon; G R Cunha
Journal:  Am J Anat       Date:  1983-10

Review 6.  Role of estrogens and progesterone in the etiology and prevention of endometrial cancer: review.

Authors:  R D Gambrell; C A Bagnell; R B Greenblatt
Journal:  Am J Obstet Gynecol       Date:  1983-07-15       Impact factor: 8.661

7.  Prognostic importance of progesterone and estrogen receptors in cancer of the uterine cervix.

Authors:  R A Potish; L B Twiggs; L L Adcock; K A Prem; J E Savage; B S Leung
Journal:  Cancer       Date:  1986-10-15       Impact factor: 6.860

8.  Cytoplasmic progesterone and estradiol receptors in normal, hyperplastic, and carcinomatous endometria: therapeutic implications.

Authors:  C E Ehrlich; P C Young; R E Cleary
Journal:  Am J Obstet Gynecol       Date:  1981-11-01       Impact factor: 8.661

9.  Nuclear and cytoplasmic oestrogen receptors in squamous carcinoma of the cervix.

Authors:  W P Soutter; R J Pegoraro; R W Green-Thompson; D V Naidoo; S M Joubert; R H Philpott
Journal:  Br J Cancer       Date:  1981-08       Impact factor: 7.640

  9 in total

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