Literature DB >> 16195558

Crystal structure of the Yersinia type III secretion protein YscE.

Jason Phan1, Brian P Austin, David S Waugh.   

Abstract

The plague-causing bacterium Yersinia pestis utilizes a contact-dependent (type III) secretion system (T3SS) to transport virulence factors from the bacterial cytosol directly into the interior of mammalian cells where they interfere with signal transduction pathways that mediate phagocytosis and the inflammatory response. The type III secretion apparatus is composed of 20-25 different Yersinia secretion (Ysc) proteins. We report here the structure of YscE, the smallest Ysc protein, which is a dimer in solution. The probable mode of oligomerization is discussed.

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Year:  2005        PMID: 16195558      PMCID: PMC2253283          DOI: 10.1110/ps.051706105

Source DB:  PubMed          Journal:  Protein Sci        ISSN: 0961-8368            Impact factor:   6.725


  12 in total

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Authors:  H M Berman; J Westbrook; Z Feng; G Gilliland; T N Bhat; H Weissig; I N Shindyalov; P E Bourne
Journal:  Nucleic Acids Res       Date:  2000-01-01       Impact factor: 16.971

2.  ARP/wARP's model-building algorithms. I. The main chain.

Authors:  Richard J Morris; Anastassis Perrakis; Victor S Lamzin
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  2002-05-29

Review 3.  Type III secretion systems and bacterial flagella: insights into their function from structural similarities.

Authors:  Ariel Blocker; Kaoru Komoriya; Shin-Ichi Aizawa
Journal:  Proc Natl Acad Sci U S A       Date:  2003-03-11       Impact factor: 11.205

4.  Refinement of macromolecular structures by the maximum-likelihood method.

Authors:  G N Murshudov; A A Vagin; E J Dodson
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  1997-05-01

5.  Raster3D Version 2.0. A program for photorealistic molecular graphics.

Authors:  E A Merritt; M E Murphy
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  1994-11-01

6.  Improved methods for building protein models in electron density maps and the location of errors in these models.

Authors:  T A Jones; J Y Zou; S W Cowan; M Kjeldgaard
Journal:  Acta Crystallogr A       Date:  1991-03-01       Impact factor: 2.290

Review 7.  Process of protein transport by the type III secretion system.

Authors:  Partho Ghosh
Journal:  Microbiol Mol Biol Rev       Date:  2004-12       Impact factor: 11.056

8.  Crystallography & NMR system: A new software suite for macromolecular structure determination.

Authors:  A T Brünger; P D Adams; G M Clore; W L DeLano; P Gros; R W Grosse-Kunstleve; J S Jiang; J Kuszewski; M Nilges; N S Pannu; R J Read; L M Rice; T Simonson; G L Warren
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  1998-09-01

9.  Protein structure comparison by alignment of distance matrices.

Authors:  L Holm; C Sander
Journal:  J Mol Biol       Date:  1993-09-05       Impact factor: 5.469

10.  Automated MAD and MIR structure solution.

Authors:  T C Terwilliger; J Berendzen
Journal:  Acta Crystallogr D Biol Crystallogr       Date:  1999-04
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  11 in total

Review 1.  Protein export according to schedule: architecture, assembly, and regulation of type III secretion systems from plant- and animal-pathogenic bacteria.

Authors:  Daniela Büttner
Journal:  Microbiol Mol Biol Rev       Date:  2012-06       Impact factor: 11.056

2.  Structural characterization of the Yersinia pestis type III secretion system needle protein YscF in complex with its heterodimeric chaperone YscE/YscG.

Authors:  Ping Sun; Joseph E Tropea; Brian P Austin; Scott Cherry; David S Waugh
Journal:  J Mol Biol       Date:  2008-01-05       Impact factor: 5.469

3.  Chaperone-mediated secretion switching from early to middle substrates in the type III secretion system encoded by Salmonella pathogenicity island 2.

Authors:  Akiko Takaya; Hikari Takeda; Shogo Tashiro; Hiroto Kawashima; Tomoko Yamamoto
Journal:  J Biol Chem       Date:  2019-01-16       Impact factor: 5.157

4.  Cochaperone interactions in export of the type III needle component PscF of Pseudomonas aeruginosa.

Authors:  Sophie Plé; Viviana Job; Andréa Dessen; Ina Attree
Journal:  J Bacteriol       Date:  2010-05-21       Impact factor: 3.490

5.  Structure of AscE and induced burial regions in AscE and AscG upon formation of the chaperone needle-subunit complex of type III secretion system in Aeromonas hydrophila.

Authors:  Yih Wan Tan; Hong Bing Yu; Ka Yin Leung; J Sivaraman; Yu-Keung Mok
Journal:  Protein Sci       Date:  2008-07-28       Impact factor: 6.725

6.  The Skap-hom dimerization and PH domains comprise a 3'-phosphoinositide-gated molecular switch.

Authors:  Kenneth D Swanson; Yong Tang; Derek F Ceccarelli; Florence Poy; Jan P Sliwa; Benjamin G Neel; Michael J Eck
Journal:  Mol Cell       Date:  2008-11-21       Impact factor: 17.970

7.  Molecular model of a type III secretion system needle: Implications for host-cell sensing.

Authors:  Janet E Deane; Pietro Roversi; Frank S Cordes; Steven Johnson; Roma Kenjale; Sarah Daniell; Frank Booy; William D Picking; Wendy L Picking; Ariel J Blocker; Susan M Lea
Journal:  Proc Natl Acad Sci U S A       Date:  2006-08-03       Impact factor: 11.205

8.  Crystal structure of the heteromolecular chaperone, AscE-AscG, from the type III secretion system in Aeromonas hydrophila.

Authors:  Chiradip Chatterjee; Sundramurthy Kumar; Smarajit Chakraborty; Yih Wan Tan; Ka Yin Leung; J Sivaraman; Yu-Keung Mok
Journal:  PLoS One       Date:  2011-04-29       Impact factor: 3.240

9.  Self-chaperoning of the type III secretion system needle tip proteins IpaD and BipD.

Authors:  Steven Johnson; Pietro Roversi; Marianela Espina; Andrew Olive; Janet E Deane; Susan Birket; Terry Field; William D Picking; Ariel J Blocker; Edouard E Galyov; Wendy L Picking; Susan M Lea
Journal:  J Biol Chem       Date:  2006-10-31       Impact factor: 5.157

Review 10.  Bacterial secretion chaperones: the mycobacterial type VII case.

Authors:  Trang H Phan; Edith N G Houben
Journal:  FEMS Microbiol Lett       Date:  2018-09-01       Impact factor: 2.742

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