| Literature DB >> 16194860 |
W Lösche1.
Abstract
Tissue factor (TF) is the most important initiator of intravascular coagulation. This article will review published evidence on the contribution of platelets to TF exposure to the circulating blood. The following mechanisms will be discussed: decryption of monocyte TF by platelets, contribution of platelets to TF expression in leukocytes, platelet-derived TF and its procoagulant activity, and activation of circulating TF by platelets.Entities:
Mesh:
Substances:
Year: 2005 PMID: 16194860 DOI: 10.1080/09537100500140190
Source DB: PubMed Journal: Platelets ISSN: 0953-7104 Impact factor: 3.862