Literature DB >> 16193137

Direct asymmetric aldol-Tishchenko reaction of aliphatic ketones catalyzed by syn-aminoalcohol-Yb(III) complexes.

Jacek Mlynarski1, Joanna Jankowska, Bartosz Rakiel.   

Abstract

The asymmetric direct aldol condensation of aldehydes with ethyl- and propylketones is catalyzed by syn-alpha-aminoalcohol-Yb(OTf)3 complexes, yielding the anti-1,3-diol monoesters with high diastereocontrol and good enantioselectivity. Three adjacent stereogenic centers are created in a simultaneous aldol condensation and Evans-Tishchenko reduction in an acyclic system.

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Year:  2005        PMID： 16193137     DOI： 10.1039/b509505k

Source DB:  PubMed          Journal:  Chem Commun (Camb)        ISSN： 1359-7345            Impact factor:   6.222


  2 in total

1.  Comparative study of regioselective synthesis of beta-aminoalcohols under solventless conditions catalyzed by sulfated zirconia and SZ/MCM-41.

Authors:  Guillermo Negrón-Silva; C Xochitl Hernández-Reyes; Deyanira Angeles-Beltrán; Leticia Lomas-Romero; Eduardo González-Zamora; Juan Méndez-Vivar
Journal:  Molecules       Date:  2007-11-15       Impact factor: 4.411

2.  Catalytic enantioselective intramolecular Tishchenko reaction of meso-dialdehyde: synthesis of (S)-cedarmycins.

Authors:  Nobuki Kishi; Yuki Adachi; Rui Jiang; Takahiro Doi; Da-Yang Zhou; Kaori Asano; Yasushi Obora; Takayoshi Suzuki; Hiroaki Sasai; Takeyuki Suzuki
Journal:  RSC Adv       Date:  2021-03-22       Impact factor: 3.361
  2 in total

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