BACKGROUND: Thermoregulation problems, resulting in hypo- or hyperthermia, have been infrequently reported in children with Prader Willi syndrome (PWS), yet their clinical details remained unknown. METHODS: The clinical characteristics of three infants with PWS are reported. RESULTS: Etiologies of high fever could not be identified in three children with PWS. One of these children was also admitted to the intensive care unit with extremely high body temperature in a life-threatening condition, similar to septic shock, without a plausible explanation. CONCLUSION: Hyperthermia may be a part of the clinical spectrum in young infants with PWS and should be carefully monitored, since it may cause life-threatening complications.
BACKGROUND: Thermoregulation problems, resulting in hypo- or hyperthermia, have been infrequently reported in children with Prader Willi syndrome (PWS), yet their clinical details remained unknown. METHODS: The clinical characteristics of three infants with PWS are reported. RESULTS: Etiologies of high fever could not be identified in three children with PWS. One of these children was also admitted to the intensive care unit with extremely high body temperature in a life-threatening condition, similar to septic shock, without a plausible explanation. CONCLUSION:Hyperthermia may be a part of the clinical spectrum in young infants with PWS and should be carefully monitored, since it may cause life-threatening complications.
Authors: Douglas C Bittel; Nataliya Kibiryeva; Steven G McNulty; Daniel J Driscoll; Merlin G Butler; Robert A White Journal: Am J Med Genet A Date: 2007-03-01 Impact factor: 2.802
Authors: David M Golding; Daniel J Rees; Jennifer R Davies; Dinko Relkovic; Hannah V Furby; Irina A Guschina; Anna L Hopkins; Jeffrey S Davies; James L Resnick; Anthony R Isles; Timothy Wells Journal: J Endocrinol Date: 2016-10-31 Impact factor: 4.286