Literature DB >> 16190712

Total synthesis of (-)-scabronine G, an inducer of neurotrophic factor production.

Stephen P Waters1, Yuan Tian, Yue-Ming Li, Samuel J Danishefsky.   

Abstract

The total synthesis of (-)-scabronine G has been achieved in a concise manner from the (-)-Wieland-Miescher ketone. Scabronine G and its more potent methyl ester (also prepared) display activity as nonpeptidyl inducers of nerve growth factor production.

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Year:  2005        PMID： 16190712     DOI： 10.1021/ja055220x

Source DB:  PubMed          Journal:  J Am Chem Soc        ISSN： 0002-7863            Impact factor:   15.419


  17 in total

Review 1.  Neurotrophic natural products: chemistry and biology.

Authors:  Jing Xu; Michelle H Lacoske; Emmanuel A Theodorakis
Journal:  Angew Chem Int Ed Engl       Date:  2013-12-18       Impact factor: 15.336

2.  Pattern recognition analysis in complex molecule synthesis and the preparation of iso-Diels-Alder motifs.

Authors:  Feng Peng; Robin E Grote; Rebecca M Wilson; Samuel J Danishefsky
Journal:  Proc Natl Acad Sci U S A       Date:  2013-06-19       Impact factor: 11.205

3.  Traceless chiral auxiliaries for the allene ether Nazarov cyclization.

Authors:  April R Banaag; Marcus A Tius
Journal:  J Org Chem       Date:  2008-09-23       Impact factor: 4.354

4.  Synthetic Studies toward the Hamigerans with a 6-7-5 Tricyclic Core.

Authors:  Baiyang Jiang; Mingji Dai
Journal:  Org Lett       Date:  2020-05-13       Impact factor: 6.005

5.  Neurotrophic peptide aldehydes: solid phase synthesis of fellutamide B and a simplified analog.

Authors:  John S Schneekloth; John L Sanders; John Hines; Craig M Crews
Journal:  Bioorg Med Chem Lett       Date:  2006-05-11       Impact factor: 2.823

6.  Concise total syntheses of the Lycopodium alkaloids (+/-)-nankakurines A and B via luciduline.

Authors:  Xiayun Cheng; Stephen P Waters
Journal:  Org Lett       Date:  2010-01-15       Impact factor: 6.005

7.  Illicium sesquiterpenes: divergent synthetic strategy and neurotrophic activity studies.

Authors:  Lynnie Trzoss; Jing Xu; Michelle H Lacoske; William C Mobley; Emmanuel A Theodorakis
Journal:  Chemistry       Date:  2013-03-22       Impact factor: 5.236

Review 8.  Synthetic efforts toward cyathane diterpenoid natural products.

Authors:  John A Enquist; Brian M Stoltz
Journal:  Nat Prod Rep       Date:  2009-03-16       Impact factor: 13.423

9.  Enantioselective total syntheses of nankakurines A and B: confirmation of structure and establishment of absolute configuration.

Authors:  Bradley L Nilsson; Larry E Overman; Javier Read de Alaniz; Jason M Rohde
Journal:  J Am Chem Soc       Date:  2008-08-02       Impact factor: 15.419

10.  Interrupting the Nazarov cyclization with indoles.

Authors:  Ashok K Basak; Marcus A Tius
Journal:  Org Lett       Date:  2008-08-23       Impact factor: 6.005
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