Literature DB >> 16189135

Lower nitric oxide susceptibility of trivalent antimony-resistant amastigotes of Leishmania infantum.

P Holzmuller1, D Sereno, J-L Lemesre.   

Abstract

We previously documented the induction of Leishmania amastigote apoptosis by trivalent antimony (SbIII) and nitric oxide (NO). We demonstrate here that SbIII-resistant amastigotes were resistant to NO toxicity when delivered extracellularly by NO donors or intracellularly via macrophage activation. Shared biochemical targets for SbIII and NO resistance in Leishmania are discussed.

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Year:  2005        PMID： 16189135      PMCID： PMC1251519          DOI： 10.1128/AAC.49.10.4406-4409.2005

Source DB:  PubMed          Journal:  Antimicrob Agents Chemother        ISSN： 0066-4804            Impact factor:   5.191


  25 in total

1.  Axenically cultured amastigote forms as an in vitro model for investigation of antileishmanial agents.

Authors:  D Sereno; J L Lemesre
Journal:  Antimicrob Agents Chemother       Date:  1997-05       Impact factor: 5.191

2.  Fallibility of Griess (nitrite) test.

Authors:  J B Roy; R G Wilkerson
Journal:  Urology       Date:  1984-03       Impact factor: 2.649

3.  Successful therapy of chronic, nonhealing murine cutaneous leishmaniasis with sodium stibogluconate and gamma interferon depends on continued interleukin-12 production.

Authors:  J Li; S Sutterwala; J P Farrell
Journal:  Infect Immun       Date:  1997-08       Impact factor: 3.441

4.  Canine visceral leishmaniasis: successful chemotherapy induces macrophage antileishmanial activity via the L-arginine nitric oxide pathway.

Authors:  I Vouldoukis; J C Drapier; A K Nüssler; Y Tselentis; O A Da Silva; M Gentilini; D M Mossalayi; L Monjour; B Dugas
Journal:  Antimicrob Agents Chemother       Date:  1996-01       Impact factor: 5.191

5.  Glutathione-induced conversion of pentavalent antimony to trivalent antimony in meglumine antimoniate.

Authors:  F Frézard; C Demicheli; C S Ferreira; M A Costa
Journal:  Antimicrob Agents Chemother       Date:  2001-03       Impact factor: 5.191

6.  Albumin nitrosylated by activated macrophages possesses antiparasitic effects neutralized by anti-NO-acetylated-cysteine antibodies.

Authors:  S Mnaimneh; M Geffard; B Veyret; P Vincendeau
Journal:  J Immunol       Date:  1997-01-01       Impact factor: 5.422

7.  In vitro and in vivo resistance of Leishmania infantum to meglumine antimoniate: a study of 37 strains collected from patients with visceral leishmaniasis.

Authors:  F Faraut-Gambarelli; R Piarroux; M Deniau; B Giusiano; P Marty; G Michel; B Faugère; H Dumon
Journal:  Antimicrob Agents Chemother       Date:  1997-04       Impact factor: 5.191

8.  Roles of endogenous gamma interferon and macrophage microbicidal mechanisms in host response to chemotherapy in experimental visceral leishmaniasis.

Authors:  H W Murray; S Delph-Etienne
Journal:  Infect Immun       Date:  2000-01       Impact factor: 3.441

9.  Trypanothione overproduction and resistance to antimonials and arsenicals in Leishmania.

Authors:  R Mukhopadhyay; S Dey; N Xu; D Gage; J Lightbody; M Ouellette; B P Rosen
Journal:  Proc Natl Acad Sci U S A       Date:  1996-09-17       Impact factor: 11.205

10.  Pentostam (sodium stibogluconate); a 50-year personal reminiscence.

Authors:  L G Goodwin
Journal:  Trans R Soc Trop Med Hyg       Date:  1995 May-Jun       Impact factor: 2.184
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  13 in total

1.  Cross-resistance of Leishmania infantum isolates to nitric oxide from patients refractory to antimony treatment, and greater tolerance to antileishmanial responses by macrophages.

Authors:  Tatiana R de Moura; Micheli Luize Barbosa Santos; Juciene M Braz; Luis Felipe V C Santos; Matheus T Aragão; Fabricia A de Oliveira; Priscila L Santos; Ângela Maria da Silva; Amélia Ribeiro de Jesus; Roque P de Almeida
Journal:  Parasitol Res       Date:  2016-02       Impact factor: 2.289

Review 2.  Leishmania antimony resistance: what we know what we can learn from the field.

Authors:  Khatima Aït-Oudhia; Elodie Gazanion; Baptiste Vergnes; Bruno Oury; Denis Sereno
Journal:  Parasitol Res       Date:  2011-07-29       Impact factor: 2.289

3.  Fatty acid profiles in Leishmania spp. isolates with natural resistance to nitric oxide and trivalent antimony.

Authors:  Alana Freire de Azevedo; Jorge Luís de Lisboa Dutra; Micheli Luize Barbosa Santos; Darlisson de Alexandria Santos; Péricles Barreto Alves; Tatiana Rodrigues de Moura; Roque Pacheco de Almeida; Marcelo Ferreira Fernandes; Ricardo Scher; Roberta Pereira Miranda Fernandes
Journal:  Parasitol Res       Date:  2013-10-06       Impact factor: 2.289

4.  Linking in vitro and in vivo survival of clinical Leishmania donovani strains.

Authors:  Manu Vanaerschot; Ilse Maes; Meriem Ouakad; Vanessa Adaui; Louis Maes; Simonne De Doncker; Suman Rijal; François Chappuis; Jean-Claude Dujardin; Saskia Decuypere
Journal:  PLoS One       Date:  2010-08-17       Impact factor: 3.240

5.  Resistance of Leishmania (Viannia) braziliensis to nitric oxide: correlation with antimony therapy and TNF-alpha production.

Authors:  Anselmo S Souza; Angela Giudice; Júlia Mb Pereira; Luís H Guimarães; Amelia R de Jesus; Tatiana R de Moura; Mary E Wilson; Edgar M Carvalho; Roque P Almeida
Journal:  BMC Infect Dis       Date:  2010-07-15       Impact factor: 3.090

6.  Miltefosine (hexadecylphosphocholine) inhibits cytochrome c oxidase in Leishmania donovani promastigotes.

Authors:  Juan Román Luque-Ortega; Luis Rivas
Journal:  Antimicrob Agents Chemother       Date:  2007-02-05       Impact factor: 5.191

7.  Antimony resistance and environment: Elusive links to explore during Leishmania life cycle.

Authors:  Denis Sereno; Carla Maia; Khatima Aït-Oudhia
Journal:  Int J Parasitol Drugs Drug Resist       Date:  2012-09-03       Impact factor: 4.077

8.  Resistance of Leishmania (Viannia) Panamensis to Meglumine Antimoniate or Miltefosine Modulates Neutrophil Effector Functions.

Authors:  Ivo B Regli; Olga Lucía Fernández; Berenice Martínez-Salazar; Maria Adelaida Gómez; Nancy Gore Saravia; Fabienne Tacchini-Cottier
Journal:  Front Immunol       Date:  2018-12-21       Impact factor: 7.561

9.  Canine leishmaniasis in Southern Italy: a role for nitric oxide released from activated macrophages in asymptomatic infection?

Authors:  Maria A Panaro; Olga Brandonisio; Donato de Caprariis; Pasqua Cavallo; Antonia Cianciulli; Vincenzo Mitolo; Domenico Otranto
Journal:  Parasit Vectors       Date:  2008-05-09       Impact factor: 3.876

10.  Leishmania amazonensis amastigotes highly express a tryparedoxin peroxidase isoform that increases parasite resistance to macrophage antimicrobial defenses and fosters parasite virulence.

Authors:  Calvin A Henard; Eric D Carlsen; Christie Hay; Peter E Kima; Lynn Soong
Journal:  PLoS Negl Trop Dis       Date:  2014-07-17
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