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Literature DB >> 16189127

Macrolide resistance mediated by a Bifidobacterium breve membrane protein.

Abelardo Margolles¹, José Antonio Moreno, Douwe van Sinderen, Clara G de Los Reyes-Gavilán.

Abstract

A gene coding for a hypothetical membrane protein from Bifidobacterium breve was expressed in Lactococcus lactis. Immunoblotting demonstrated that this protein is located in the membrane. Phenotypical changes in sensitivity towards 21 antibiotics were determined. The membrane protein-expressing cells showed higher levels of resistance to several macrolides.

Entities: Chemical Species

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Year: 2005 PMID： 16189127 PMCID： PMC1251533 DOI： 10.1128/AAC.49.10.4379-4381.2005

Source DB: PubMed Journal: Antimicrob Agents Chemother ISSN： 0066-4804 Impact factor: 5.191

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