Literature DB >> 16188288

In vivo confocal imaging of the retina in animal models using scanning laser ophthalmoscopy.

Mathias W Seeliger1, Susanne C Beck, Naira Pereyra-Muñoz, Susann Dangel, Jen-Yue Tsai, Ulrich F O Luhmann, Serge A van de Pavert, Jan Wijnholds, Marijana Samardzija, Andreas Wenzel, Eberhart Zrenner, Kristina Narfström, Edda Fahl, Naoyuki Tanimoto, Niyazi Acar, Felix Tonagel.   

Abstract

Scanning-laser ophthalmoscopy is a technique for confocal imaging of the eye in vivo. The use of lasers of different wavelengths allows to obtain information about specific tissues and layers due to their reflection and transmission characteristics. In addition, fluorescent dyes excitable in the blue and infrared range offer a unique access to the vascular structures associated with each layer. In animal models, a further enhancement in specificity can be obtained by GFP expression under control of tissue-specific promotors. Important fields of application are studies in retinal degenerations and the follow-up of therapeutic intervention.

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Year:  2005        PMID: 16188288     DOI: 10.1016/j.visres.2005.08.014

Source DB:  PubMed          Journal:  Vision Res        ISSN: 0042-6989            Impact factor:   1.886


  79 in total

1.  Optimization of in vivo confocal autofluorescence imaging of the ocular fundus in mice and its application to models of human retinal degeneration.

Authors:  Peter Charbel Issa; Mandeep S Singh; Daniel M Lipinski; Ngaihang V Chong; François C Delori; Alun R Barnard; Robert E MacLaren
Journal:  Invest Ophthalmol Vis Sci       Date:  2012-02-29       Impact factor: 4.799

2.  Multimodal photoacoustic ophthalmoscopy in mouse.

Authors:  Wei Song; Qing Wei; Liang Feng; Vijay Sarthy; Shuliang Jiao; Xiaorong Liu; Hao F Zhang
Journal:  J Biophotonics       Date:  2012-05-31       Impact factor: 3.207

3.  Increased neovascularization in mice lacking tissue inhibitor of metalloproteinases-3.

Authors:  Quteba Ebrahem; Jian Hua Qi; Masahiko Sugimoto; Mariya Ali; Jonathan E Sears; Alecia Cutler; Rama Khokha; Amit Vasanji; Bela Anand-Apte
Journal:  Invest Ophthalmol Vis Sci       Date:  2011-08-03       Impact factor: 4.799

Review 4.  Cellular and physiological mechanisms underlying blood flow regulation in the retina and choroid in health and disease.

Authors:  Joanna Kur; Eric A Newman; Tailoi Chan-Ling
Journal:  Prog Retin Eye Res       Date:  2012-05-03       Impact factor: 21.198

5.  Spectral domain optical coherence tomography in mouse models of retinal degeneration.

Authors:  Gesine Huber; Susanne C Beck; Christian Grimm; Ayse Sahaboglu-Tekgoz; Francois Paquet-Durand; Andreas Wenzel; Peter Humphries; T Michael Redmond; Mathias W Seeliger; M Dominik Fischer
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-08-06       Impact factor: 4.799

Review 6.  In vivo imaging methods to assess glaucomatous optic neuropathy.

Authors:  Brad Fortune
Journal:  Exp Eye Res       Date:  2015-06-03       Impact factor: 3.467

7.  Bisretinoids mediate light sensitivity resulting in photoreceptor cell degeneration in mice lacking the receptor tyrosine kinase Mer.

Authors:  Jin Zhao; Keiko Ueda; Marina Riera; Hye Jin Kim; Janet R Sparrow
Journal:  J Biol Chem       Date:  2018-10-23       Impact factor: 5.157

8.  Funduscopy in adult zebrafish and its application to isolate mutant strains with ocular defects.

Authors:  Markus Tschopp; Masanari Takamiya; Kara L Cerveny; Gaia Gestri; Oliver Biehlmaier; Stephen W Wilson; Uwe Strähle; Stephan C F Neuhauss
Journal:  PLoS One       Date:  2010-11-05       Impact factor: 3.240

9.  GFAP-driven GFP expression in activated mouse Müller glial cells aligning retinal blood vessels following intravitreal injection of AAV2/6 vectors.

Authors:  Wendy M Aartsen; Koen W R van Cleef; Lucie P Pellissier; Robert M Hoek; Rogier M Vos; Bas Blits; Erich M E Ehlert; Kamaljit S Balaggan; Robin R Ali; Joost Verhaagen; Jan Wijnholds
Journal:  PLoS One       Date:  2010-08-24       Impact factor: 3.240

10.  Noninvasive, in vivo assessment of mouse retinal structure using optical coherence tomography.

Authors:  M Dominik Fischer; Gesine Huber; Susanne C Beck; Naoyuki Tanimoto; Regine Muehlfriedel; Edda Fahl; Christian Grimm; Andreas Wenzel; Charlotte E Remé; Serge A van de Pavert; Jan Wijnholds; Marek Pacal; Rod Bremner; Mathias W Seeliger
Journal:  PLoS One       Date:  2009-10-19       Impact factor: 3.240

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