| Literature DB >> 16188288 |
Mathias W Seeliger1, Susanne C Beck, Naira Pereyra-Muñoz, Susann Dangel, Jen-Yue Tsai, Ulrich F O Luhmann, Serge A van de Pavert, Jan Wijnholds, Marijana Samardzija, Andreas Wenzel, Eberhart Zrenner, Kristina Narfström, Edda Fahl, Naoyuki Tanimoto, Niyazi Acar, Felix Tonagel.
Abstract
Scanning-laser ophthalmoscopy is a technique for confocal imaging of the eye in vivo. The use of lasers of different wavelengths allows to obtain information about specific tissues and layers due to their reflection and transmission characteristics. In addition, fluorescent dyes excitable in the blue and infrared range offer a unique access to the vascular structures associated with each layer. In animal models, a further enhancement in specificity can be obtained by GFP expression under control of tissue-specific promotors. Important fields of application are studies in retinal degenerations and the follow-up of therapeutic intervention.Entities:
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Year: 2005 PMID: 16188288 DOI: 10.1016/j.visres.2005.08.014
Source DB: PubMed Journal: Vision Res ISSN: 0042-6989 Impact factor: 1.886