Literature DB >> 16182753

Improvements in hepatic parenchymal transection for living related liver donor.

S Gruttadauria1, L Mandalà, F Vasta, D Cintorino, A Musumeci, W Marsh, A Marcos, B Gridelli.   

Abstract

INTRODUCTION: To eliminate mortality and morbidity risk in living related liver donors, we developed a new surgical technique to resect hepatic parenchyma using an ultrasonic surgical aspirator in association with a monopolar floating ball cautery.
METHODS: We performed 17 right hepatectomies and 2 left hepatectomies using this technique. We performed a retrospective analysis of perioperative mortality, length of hospitalization (LOS), blood transfused during surgery (IBT), intraoperative blood lost (IBL), biliary complications (BC), and aspartate aminotransferase (AST)/alanine aminotransferase (ALT) peak in the first postoperative week. This group of patients (Group A) was compared, using the analysis of variance (ANOVA) test (P < .05) with 2 different groups of 19 patients: Group B with liver neoplasms that had the same technique as Group A, and Group C wherein a crushing clamp technique was used.
RESULTS: All of the analyzed variables showed significative statistical differences, especially between Group A and Group C (IBL, P < .000; IBT, P < .006; LOS, P < .028; BC, P < .000; AST peak, P < .041; and ALT peak, P < .023). DISCUSSION: The association of these 2 techniques seems to reduce the LOS, and the need for intraoperative blood transfusions. Moreover, the surgical complications (biliary leaks) and the postoperative parenchymal cytonecrosis seem to be less using this technique.

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Year:  2005        PMID: 16182753     DOI: 10.1016/j.transproceed.2005.06.062

Source DB:  PubMed          Journal:  Transplant Proc        ISSN: 0041-1345            Impact factor:   1.066


  3 in total

1.  Right hepatic lobe living donation: a 12 years single Italian center experience.

Authors:  Salvatore Gruttadauria; Duilio Pagano; Davide Cintorino; Antonio Arcadipane; Mario Traina; Riccardo Volpes; Angelo Luca; Giovanni Vizzini; Bruno Gridelli; Marco Spada
Journal:  World J Gastroenterol       Date:  2013-10-14       Impact factor: 5.742

2.  Analysis of surgical and perioperative complications in seventy-five right hepatectomies for living donor liver transplantation.

Authors:  Salvatore Gruttadauria; James Wallis Marsh; Giovan Battista Vizzini; Fabrizio di Francesco; Angelo Luca; Riccardo Volpes; Amadeo Marcos; Bruno Gridelli
Journal:  World J Gastroenterol       Date:  2008-05-28       Impact factor: 5.742

3.  Role of basiliximab in the prevention of acute cellular rejection in adult to adult living-related liver transplantation: a single center experience.

Authors:  S Gruttadauria; L Mandalà; D Biondo; M Spampinato; V Lamonaca; R Volpes; G Vizzini; Jw Marsh; A Marcos; B Gridelli
Journal:  Biologics       Date:  2007-03
  3 in total

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