Literature DB >> 16181948

Outcome after traumatic brain injury: effects of aging on recovery.

Julie A Testa1, James F Malec, Anne M Moessner, Allen W Brown.   

Abstract

OBJECTIVE: To identify differences in outcome after traumatic brain injury (TBI) compared with orthopedic injuries as a function of age.
DESIGN: Longitudinal data analyses from an inception cohort.
SETTING: Outpatient rehabilitation program. PARTICIPANTS: Eighty-two orthopedic injury patients and 195 TBI patients.
INTERVENTIONS: Not applicable. MAIN OUTCOME MEASURES: Independent living, employment, and level of functioning 1 to 2 years after injury.
RESULTS: Older patients and those with TBI were more likely to have increased dependence postinjury. Older TBI patients were more likely to have changes in employment status compared with orthopedic injury patients younger or TBI. The Mayo-Portland Adaptability Inventory and Disability Rating Scale were moderately predictive of level of functioning, return to employment, and independent living status 1 to 2 years postinjury. Injury severity was only mildly predictive of outcome.
CONCLUSIONS: The effect of age on outcome affects recovery from neurologic injuries and, to a lesser extent, orthopedic injuries. Outcome after TBI is best predicted by patients' age and estimates of level of function at discharge. Findings suggest that older patients and those with TBI have a greater likelihood of becoming physically and financially dependent on others. Rehabilitation efforts should focus on maximizing levels of independence to limit financial and emotional costs to patients and their families.

Entities:  

Mesh:

Year:  2005        PMID: 16181948     DOI: 10.1016/j.apmr.2005.03.010

Source DB:  PubMed          Journal:  Arch Phys Med Rehabil        ISSN: 0003-9993            Impact factor:   3.966


  14 in total

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2.  Accumulation of health disorders as a systemic measure of aging: Findings from the NLTCS data.

Authors:  Alexander Kulminski; Anatoli Yashin; Svetlana Ukraintseva; Igor Akushevich; Konstantin Arbeev; Kenneth Land; Kenneth Manton
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3.  Traumatic brain injury in aged animals increases lesion size and chronically alters microglial/macrophage classical and alternative activation states.

Authors:  Alok Kumar; Bogdan A Stoica; Boris Sabirzhanov; Mark P Burns; Alan I Faden; David J Loane
Journal:  Neurobiol Aging       Date:  2012-12-27       Impact factor: 4.673

4.  Impact of aging on the immune response to traumatic brain injury (AIm:TBI) study protocol.

Authors:  Hilaire J Thompson; Frederick Rivara; Kyra J Becker; Ronald Maier; Nancy Temkin
Journal:  Inj Prev       Date:  2019-09-03       Impact factor: 2.399

5.  Mild cognitive impairment and structural brain abnormalities in a sexagenarian with a history of childhood traumatic brain injury.

Authors:  John Darrell Van Horn; Andrei Irimia; Carinna M Torgerson; Avnish Bhattrai; Zachary Jacokes; Paul M Vespa
Journal:  J Neurosci Res       Date:  2017-05-20       Impact factor: 4.164

6.  Long-term survival after traumatic brain injury: a population-based analysis controlled for nonhead trauma.

Authors:  Allen W Brown; Cynthia L Leibson; Jay Mandrekar; Jeanine E Ransom; James F Malec
Journal:  J Head Trauma Rehabil       Date:  2014 Jan-Feb       Impact factor: 2.710

7.  Impact of age on long-term recovery from traumatic brain injury.

Authors:  Carlos D Marquez de la Plata; Tessa Hart; Flora M Hammond; Alan B Frol; Anne Hudak; Caryn R Harper; Therese M O'Neil-Pirozzi; John Whyte; Mary Carlile; Ramon Diaz-Arrastia
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8.  Impaired expression of neuroprotective molecules in the HIF-1alpha pathway following traumatic brain injury in aged mice.

Authors:  Joshua Anderson; Rajat Sandhir; Eric S Hamilton; Nancy E J Berman
Journal:  J Neurotrauma       Date:  2009-09       Impact factor: 5.269

Review 9.  Aging and animal models of systemic insult: trauma, burn, and sepsis.

Authors:  Vanessa Nomellini; Christian R Gomez; Richard L Gamelli; Elizabeth J Kovacs
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10.  Predictive utility of an adapted Marshall head CT classification scheme after traumatic brain injury.

Authors:  Allen W Brown; Christopher R Pretz; Kathleen R Bell; Flora M Hammond; David B Arciniegas; Yelena G Bodien; Kristen Dams-O'Connor; Joseph T Giacino; Tessa Hart; Douglas Johnson-Greene; Robert G Kowalski; William C Walker; Alan Weintraub; Ross Zafonte
Journal:  Brain Inj       Date:  2019-01-19       Impact factor: 2.311

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