Literature DB >> 16181594

Postoperative parathyroid hormone levels in conjunction with corrected calcium values as a predictor of post-thyroidectomy hypocalcemia: review of outcomes 1 year after the implementation of a new protocol.

Richard J Payne1, Michael P Hier, Valérie Côté, Michael Tamilia, Elizabeth MacNamara, Martin J Black.   

Abstract

OBJECTIVES: To determine the effectiveness of post-thyroidectomy parathyroid hormone (PTH) levels in conjunction with corrected calcium values as predictors of patients at risk of developing hypocalcemia.
METHODS: This is a follow-up study reviewing the results of a newly implemented post-thyroidectomy algorithm. The changes in management from the previous protocol involve decision making based on the 12-hour corrected calcium and PTH levels, as well as the 1-hour PTH value. The study involved 120 patients separated into two groups: 60 prior to implementation of the protocol and 60 following the implementation of the protocol. Patients having completion thyroidectomy, neck dissections, or parathyroidectomy were excluded.
RESULTS: Since the implementation of the new protocol, there has been a reduction in the rate of transient hypocalcemia (25% to 12%; p = .059), fewer blood tests (23 to 15 per patient), and earlier patient discharges.
CONCLUSIONS: The new algorithm is effective in detecting patients who are not at risk of developing hypocalcemia at 12 hours. This has led to significant cost savings at our institution. Moreover, calcium supplementation based on the 1-hour PTH level has coincided with a reduction in cases of transient hypocalcemia.

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Year:  2005        PMID: 16181594     DOI: 10.2310/7070.2005.34505

Source DB:  PubMed          Journal:  J Otolaryngol        ISSN: 0381-6605


  6 in total

1.  Early prediction of hypocalcemia following thyroid surgery. A prospective randomized clinical trial.

Authors:  Alessandra Saba; Mauro Podda; Antonio Messina Campanella; Adolfo Pisanu
Journal:  Langenbecks Arch Surg       Date:  2017-05-20       Impact factor: 3.445

Review 2.  Early intact PTH (iPTH) is an early predictor of postoperative hypocalcemia for a safer and earlier hospital discharge: an analysis on 260 total thyroidectomies.

Authors:  Davide Inversini; Stefano Rausei; Cesare Carlo Ferrari; Francesco Frattini; Angkoon Anuwong; Hoon Yub Kim; Xiaoli Liu; Chei-Wei Wu; Wen Tian; Renbin Liu; Gianlorenzo Dionigi
Journal:  Gland Surg       Date:  2016-10

Review 3.  Evidence for the role of perioperative PTH measurement after total thyroidectomy as a predictor of hypocalcemia.

Authors:  Simon Grodski; Jonathan Serpell
Journal:  World J Surg       Date:  2008-07       Impact factor: 3.352

4.  Parathyroid hormone and serum calcium levels measurements as predictors of postoperative hypocalcemia in total thyroidectomy.

Authors:  Mohammed Algarni; Rajab Alzahrani; Gianlorenzo Dionigi; Al-Hakami Hadi; Haia AlSubayea
Journal:  Gland Surg       Date:  2017-10

5.  Comparison of parathyroid hormone kinetics in endoscopic thyroidectomy via bilateral areola with open thyroidectomy.

Authors:  Daqi Zhang; Tie Wang; Gianlorenzo Dionigi; Jiao Zhang; Yishen Zhao; Gaofeng Xue; Nan Liang; Hui Sun
Journal:  BMC Surg       Date:  2019-12-11       Impact factor: 2.102

6.  Comparison of iPTH and calcium levels between total thyroidectomy and lobectomy: a prospective study of 840 thyroid cancers with three years of follow-up.

Authors:  Xiaoli Liu; Xuehai Bian; Changlin Li; Jingwei Xin; Qingfeng Fu; Chunhai Zhang; Fang Li; Jinxi Jiang; Gianlorenzo Dionigi; Hui Sun
Journal:  Ann Transl Med       Date:  2020-10
  6 in total

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