| Literature DB >> 16181334 |
Michel Desjardins1, Mathieu Houde, Etienne Gagnon.
Abstract
Phagocytosis, the process by which cells internalize large particulate materials from their milieu and sequester them in phagosomes, plays a role in a variety of cell functions ranging from nutrition in ameba to innate and adaptive immunity in mammals. Recent findings revealed unexpected characteristics of phagosomes, highlighting how this complex organelle may have evolved, from Dictyostelium to human, to become a key player in our ability to mount an efficient immune response against a variety of intracellular pathogens.Entities:
Mesh:
Year: 2005 PMID: 16181334 DOI: 10.1111/j.0105-2896.2005.00319.x
Source DB: PubMed Journal: Immunol Rev ISSN: 0105-2896 Impact factor: 12.988