[Prognosis of patients with progressive supranuclear palsy].

Survival and prognosis were investigated in 45 patients with progressive supranuclear palsy (including 10 autopsy cases) from April, 1991 to March, 2003 in Higashi Nagoya National Hospital. The subjects were 28 males, and 17 females. Mean age at onset was 64.9 years old (45-79 years old), and median survival time was 6 years. Age at onset, sex and clinical group due to NINDS-SPSP criteria ("probable" vs "possible") were not related to survival time. Among the symptoms and signs at onset, only dysphagia was related to prognosis. Dysphagia within the first year from onset reduced survival time (p < 0.0001).