Literature DB >> 1617962

Six-month carbohydrate metabolism studies in women using oral contraceptives containing gestodene and ethinyl estradiol.

W N Spellacy1, J C Tsibris, D L Hunter-Bonner, S Smalling, R A Chez, J L Angel, W F O'Brien.   

Abstract

Twenty-five women had their carbohydrate metabolism prospectively evaluated during the six months that they used a gestodene and ethinyl estradiol monophasic oral contraceptive. Serum glucose and insulin levels were measured during a 75-gram three-hour oral glucose tolerance test. At the six-month test, the three-hour glucose and the fasting and three-hour insulin values were significantly elevated. The literature on carbohydrate metabolism during gestodene oral contraceptive use is also reviewed.

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Keywords:  Biology; Carbohydrate Metabolic Effects; Contraception; Contraceptive Agents, Estrogen--side effects; Contraceptive Agents, Female--side effects; Contraceptive Agents, Progestin--side effects; Contraceptive Agents--side effects; Contraceptive Methods--side effects; Ethinyl Estradiol--side effects; Examinations And Diagnoses; Family Planning; Gestodene--side effects; Glucose Tolerance Test; Laboratory Examinations And Diagnoses; Laboratory Procedures; Metabolic Effects; Oral Contraceptives, Combined--side effects; Oral Contraceptives, Phasic--side effects; Oral Contraceptives--side effects; Physiology; Prospective Studies; Research Methodology; Studies

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Year:  1992        PMID: 1617962     DOI: 10.1016/0010-7824(92)90104-2

Source DB:  PubMed          Journal:  Contraception        ISSN: 0010-7824            Impact factor:   3.375


  2 in total

Review 1.  Gestodene. A review of its pharmacology, efficacy and tolerability in combined contraceptive preparations.

Authors:  M I Wilde; J A Balfour
Journal:  Drugs       Date:  1995-08       Impact factor: 9.546

Review 2.  Comparative pharmacology of newer progestogens.

Authors:  H Kuhl
Journal:  Drugs       Date:  1996-02       Impact factor: 9.546

  2 in total

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