Literature DB >> 16178367

Correlation between in vitro growth rate and in vivo virulence in Aspergillus fumigatus.

Derek Paisley1, Geoffrey D Robson, David W Denning.   

Abstract

We describe a kinetic microbroth method of measuring the growth rate of Aspergillus fumigatus spectrophotometrically. Using this method, growth rates were determined for nine A. fumigatus isolates for which an LD90 value in immunosuppressed CD-1 mice had previously been obtained. Comparison of the growth rates and LD90 values of these isolates suggests that a correlation exists between the two parameters.

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Year:  2005        PMID： 16178367     DOI： 10.1080/13693780400005866

Source DB:  PubMed          Journal:  Med Mycol        ISSN： 1369-3786            Impact factor:   4.076


  27 in total

1.  Calcineurin controls growth, morphology, and pathogenicity in Aspergillus fumigatus.

Authors:  William J Steinbach; Robert A Cramer; B Zachary Perfect; Yohannes G Asfaw; Theodor C Sauer; Laura K Najvar; William R Kirkpatrick; Thomas F Patterson; Daniel K Benjamin; Joseph Heitman; John R Perfect
Journal:  Eukaryot Cell       Date:  2006-07

2.  A fungus-specific ras homolog contributes to the hyphal growth and virulence of Aspergillus fumigatus.

Authors:  Jarrod R Fortwendel; Wei Zhao; Ruchi Bhabhra; Steven Park; David S Perlin; David S Askew; Judith C Rhodes
Journal:  Eukaryot Cell       Date:  2005-12

3.  Lung eosinophil recruitment in response to Aspergillus fumigatus is correlated with fungal cell wall composition and requires γδ T cells.

Authors:  Nansalmaa Amarsaikhan; Evan M O'Dea; Angar Tsoggerel; Steven P Templeton
Journal:  Microbes Infect       Date:  2017-05-25       Impact factor: 2.700

4.  Interrogation of related clinical pan-azole-resistant Aspergillus fumigatus strains: G138C, Y431C, and G434C single nucleotide polymorphisms in cyp51A, upregulation of cyp51A, and integration and activation of transposon Atf1 in the cyp51A promoter.

Authors:  Ahmed M Albarrag; Michael J Anderson; Susan J Howard; Geoff D Robson; Peter A Warn; Dominique Sanglard; David W Denning
Journal:  Antimicrob Agents Chemother       Date:  2011-08-29       Impact factor: 5.191

5.  Divergent Protein Kinase A isoforms co-ordinately regulate conidial germination, carbohydrate metabolism and virulence in Aspergillus fumigatus.

Authors:  Kevin K Fuller; Daryl L Richie; Xizhi Feng; Karthik Krishnan; Timothy J Stephens; Kathryn A Wikenheiser-Brokamp; David S Askew; Judith C Rhodes
Journal:  Mol Microbiol       Date:  2011-01-06       Impact factor: 3.501

6.  Impaired ribosome biogenesis disrupts the integration between morphogenesis and nuclear duplication during the germination of Aspergillus fumigatus.

Authors:  Ruchi Bhabhra; Daryl L Richie; H Stanley Kim; William C Nierman; Jarrod Fortwendel; John P Aris; Judith C Rhodes; David S Askew
Journal:  Eukaryot Cell       Date:  2008-02-22

7.  Disparate proteome responses of pathogenic and nonpathogenic aspergilli to human serum measured by activity-based protein profiling (ABPP).

Authors:  Susan D Wiedner; Charles Ansong; Bobbie-Jo Webb-Robertson; LeeAnna M Pederson; Suereta Fortuin; Beth A Hofstad; Anil K Shukla; Ellen A Panisko; Richard D Smith; Aaron T Wright
Journal:  Mol Cell Proteomics       Date:  2013-04-18       Impact factor: 5.911

8.  Evolution of drug-resistant and virulent small colonies in phenotypically diverse populations of the human fungal pathogen Candida glabrata.

Authors:  Sarah J N Duxbury; Steven Bates; Robert E Beardmore; Ivana Gudelj
Journal:  Proc Biol Sci       Date:  2020-07-15       Impact factor: 5.349

9.  A fungal pH-responsive signaling pathway regulating Aspergillus adaptation and invasion into the cornea.

Authors:  Xia Hua; Xiaoyong Yuan; Kirk R Wilhelmus
Journal:  Invest Ophthalmol Vis Sci       Date:  2009-10-22       Impact factor: 4.799

10.  The sho1 sensor regulates growth, morphology, and oxidant adaptation in Aspergillus fumigatus but is not essential for development of invasive pulmonary aspergillosis.

Authors:  Yan Ma; Jianjun Qiao; Wei Liu; Zhe Wan; Xiaohong Wang; Richard Calderone; Ruoyu Li
Journal:  Infect Immun       Date:  2008-01-28       Impact factor: 3.441
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