| Literature DB >> 16178025 |
Marcus Richards1, Ian J Deary.
Abstract
The concept of reserve in neuroscience maintains that there are aspects of brain structure and function that can buffer the effects of neuropathology such that the greater the reserve, the more severe the pathology must be to cause functional impairment. This article provides a concise overview of structural and functional approaches to reserve and shows how reserve may be conceived as the sum of its lifetime input. In this context, reserve therefore provides an empirical yet general model of cognitive aging and development.Entities:
Mesh:
Year: 2005 PMID: 16178025 DOI: 10.1002/ana.20637
Source DB: PubMed Journal: Ann Neurol ISSN: 0364-5134 Impact factor: 10.422