OBJECTIVE: The objective of our study was to determine the diagnostic performance of MRI based on a HASTE sequence for the detection of pulmonary nodules in comparison with MDCT. MATERIALS AND METHODS: Thirty patients with known pulmonary nodules underwent both MRI and CT. CT of the lung served as the standard of reference and was performed on a 4-MDCT scanner using a routine protocol. MRI was performed with axial and coronal HASTE sequences using a high-performance 1.5-T MR scanner. Image data were analyzed in three steps after completion of all data acquisition. Step 1 was the analysis of all the CT image data. Step 2 was the analysis of all the MR image data while blinded to the results of the CT findings. Step 3 closed with a simultaneous review of all corresponding CT and MRI data, including a one-to-one correlation of the size and location of all the nodules that were detected. RESULTS: Compared with the sensitivity of CT, the sensitivity values for the HASTE MR sequence were as follows: 73% for lesions less than 3 mm, 86.3% for lesions between 3 and 5 mm, 95.7% for lesions between 6 and 10 mm, and 100% for lesions larger than 10 mm. The overall sensitivity of the HASTE sequence for the detection of all pulmonary lesions was 85.4%. CONCLUSION: An MRI examination that consists of a HASTE sequence allows one to detect, exclude, or monitor pulmonary lesions that are 5 mm and bigger. Suspicious lesions smaller than 5 mm still need to be validated using CT.
OBJECTIVE: The objective of our study was to determine the diagnostic performance of MRI based on a HASTE sequence for the detection of pulmonary nodules in comparison with MDCT. MATERIALS AND METHODS: Thirty patients with known pulmonary nodules underwent both MRI and CT. CT of the lung served as the standard of reference and was performed on a 4-MDCT scanner using a routine protocol. MRI was performed with axial and coronal HASTE sequences using a high-performance 1.5-T MR scanner. Image data were analyzed in three steps after completion of all data acquisition. Step 1 was the analysis of all the CT image data. Step 2 was the analysis of all the MR image data while blinded to the results of the CT findings. Step 3 closed with a simultaneous review of all corresponding CT and MRI data, including a one-to-one correlation of the size and location of all the nodules that were detected. RESULTS: Compared with the sensitivity of CT, the sensitivity values for the HASTE MR sequence were as follows: 73% for lesions less than 3 mm, 86.3% for lesions between 3 and 5 mm, 95.7% for lesions between 6 and 10 mm, and 100% for lesions larger than 10 mm. The overall sensitivity of the HASTE sequence for the detection of all pulmonary lesions was 85.4%. CONCLUSION: An MRI examination that consists of a HASTE sequence allows one to detect, exclude, or monitor pulmonary lesions that are 5 mm and bigger. Suspicious lesions smaller than 5 mm still need to be validated using CT.
Authors: Benedikt Schaarschmidt; Christian Buchbender; Benedikt Gomez; Christian Rubbert; Florian Hild; Jens Köhler; Johannes Grueneisen; Henning Reis; Verena Ruhlmann; Axel Wetter; Harald H Quick; Gerald Antoch; Philipp Heusch Journal: Eur J Nucl Med Mol Imaging Date: 2015-04-08 Impact factor: 9.236
Authors: M Regier; S Kandel; M G Kaul; B Hoffmann; H Ittrich; P M Bansmann; J Kemper; C Nolte-Ernsting; M Heller; G Adam; J Biederer Journal: Eur Radiol Date: 2006-09-30 Impact factor: 5.315