Literature DB >> 16177393

Induction of SAP7 correlates with virulence in an intravenous infection model of candidiasis but not in a vaginal infection model in mice.

Brad N Taylor1, Holger Hannemann, Miriam Sehnal, Antje Biesemeier, Anja Schweizer, Martin Röllinghoff, Klaus Schröppel.   

Abstract

SAP7 of Candida albicans is induced after vaginal infection of mice. Conversely, virulence during vaginal infection was not affected in a Deltasap7/Deltasap7 mutant strain. Only a partial virulence phenotype was detectable after intravenous injection. In conclusion, SAP7 expression does not correlate with C. albicans virulence in mice.

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Year:  2005        PMID： 16177393      PMCID： PMC1230973          DOI： 10.1128/IAI.73.10.7061-7063.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  28 in total

Review 1.  Candida albicans proteinases: resolving the mystery of a gene family.

Authors:  Bernhard Hube; Julian Naglik
Journal:  Microbiology       Date:  2001-08       Impact factor: 2.777

2.  Signaling through adenylyl cyclase is essential for hyphal growth and virulence in the pathogenic fungus Candida albicans.

Authors:  C R Rocha; K Schröppel; D Harcus; A Marcil; D Dignard; B N Taylor; D Y Thomas; M Whiteway; E Leberer
Journal:  Mol Biol Cell       Date:  2001-11       Impact factor: 4.138

3.  Profile of Candida albicans-secreted aspartic proteinase elicited during vaginal infection.

Authors:  Brad N Taylor; Peter Staib; Ayfer Binder; Antje Biesemeier; Miriam Sehnal; Martin Röllinghoff; Joachim Morschhäuser; Klaus Schröppel
Journal:  Infect Immun       Date:  2005-03       Impact factor: 3.441

4.  A triple deletion of the secreted aspartyl proteinase genes SAP4, SAP5, and SAP6 of Candida albicans causes attenuated virulence.

Authors:  D Sanglard; B Hube; M Monod; F C Odds; N A Gow
Journal:  Infect Immun       Date:  1997-09       Impact factor: 3.441

Review 5.  Germ tube growth of Candida albicans.

Authors:  N A Gow
Journal:  Curr Top Med Mycol       Date:  1997-12

6.  Evidence that members of the secretory aspartyl proteinase gene family, in particular SAP2, are virulence factors for Candida vaginitis.

Authors:  F De Bernardis; S Arancia; L Morelli; B Hube; D Sanglard; W Schäfer; A Cassone
Journal:  J Infect Dis       Date:  1999-01       Impact factor: 5.226

7.  The secreted aspartyl proteinases Sap1 and Sap2 cause tissue damage in an in vitro model of vaginal candidiasis based on reconstituted human vaginal epithelium.

Authors:  Martin Schaller; Matthias Bein; Hans C Korting; Stefan Baur; Gerald Hamm; Michel Monod; Sabine Beinhauer; Bernhard Hube
Journal:  Infect Immun       Date:  2003-06       Impact factor: 3.441

8.  Possible role of secreted proteinases in Candida albicans infections.

Authors:  B Hube
Journal:  Rev Iberoam Micol       Date:  1998-06       Impact factor: 1.044

9.  Multiplicity of genes encoding secreted aspartic proteinases in Candida species.

Authors:  M Monod; G Togni; B Hube; D Sanglard
Journal:  Mol Microbiol       Date:  1994-07       Impact factor: 3.501

10.  Isolation of the Candida albicans gene for orotidine-5'-phosphate decarboxylase by complementation of S. cerevisiae ura3 and E. coli pyrF mutations.

Authors:  A M Gillum; E Y Tsay; D R Kirsch
Journal:  Mol Gen Genet       Date:  1984
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  11 in total

1.  Quantification of the APE2 gene expression level in Candida albicans clinical isolates from patients with diagnosed fungal infections.

Authors:  M Staniszewska; M Bondaryk; K Żukowski; M Chudy
Journal:  Eur J Clin Microbiol Infect Dis       Date:  2015-04-16       Impact factor: 3.267

Review 2.  Candida albicans cell wall proteins.

Authors:  W LaJean Chaffin
Journal:  Microbiol Mol Biol Rev       Date:  2008-09       Impact factor: 11.056

3.  Limited role of secreted aspartyl proteinases Sap1 to Sap6 in Candida albicans virulence and host immune response in murine hematogenously disseminated candidiasis.

Authors:  Alexandra Correia; Ulrich Lermann; Luzia Teixeira; Filipe Cerca; Sofia Botelho; Rui M Gil da Costa; Paula Sampaio; Fátima Gärtner; Joachim Morschhäuser; Manuel Vilanova; Célia Pais
Journal:  Infect Immun       Date:  2010-08-02       Impact factor: 3.441

4.  Genetically Engineered Virus Nanofibers as an Efficient Vaccine for Preventing Fungal Infection.

Authors:  Yanyan Huai; Shuai Dong; Ye Zhu; Xin Li; Binrui Cao; Xiang Gao; Mingying Yang; Li Wang; Chuanbin Mao
Journal:  Adv Healthc Mater       Date:  2016-02-18       Impact factor: 9.933

5.  The glycosylphosphatidylinositol-anchored protease Sap9 modulates the interaction of Candida albicans with human neutrophils.

Authors:  Anke Hornbach; Antje Heyken; Lydia Schild; Bernhard Hube; Jürgen Löffler; Oliver Kurzai
Journal:  Infect Immun       Date:  2009-10-05       Impact factor: 3.441

6.  A quantitative real-time RT-PCR assay for mature C. albicans biofilms.

Authors:  Zhihong Xie; Angela Thompson; Helena Kashleva; Anna Dongari-Bagtzoglou
Journal:  BMC Microbiol       Date:  2011-05-06       Impact factor: 3.605

7.  Candida albicans possesses Sap7 as a pepstatin A-insensitive secreted aspartic protease.

Authors:  Wataru Aoki; Nao Kitahara; Natsuko Miura; Hironobu Morisaka; Yoshihiro Yamamoto; Kouichi Kuroda; Mitsuyoshi Ueda
Journal:  PLoS One       Date:  2012-02-27       Impact factor: 3.240

8.  Human serum promotes Candida albicans biofilm growth and virulence gene expression on silicone biomaterial.

Authors:  Yuthika Hemamala Samaranayake; Becky P K Cheung; Joyce Y Y Yau; Shadow K W Yeung; Lakshman P Samaranayake
Journal:  PLoS One       Date:  2013-05-21       Impact factor: 3.240

Review 9.  Candida albicans pathogenicity mechanisms.

Authors:  François L Mayer; Duncan Wilson; Bernhard Hube
Journal:  Virulence       Date:  2013-01-09       Impact factor: 5.882

10.  Candidalysin is a fungal peptide toxin critical for mucosal infection.

Authors:  David L Moyes; Duncan Wilson; Jonathan P Richardson; Selene Mogavero; Shirley X Tang; Julia Wernecke; Sarah Höfs; Remi L Gratacap; Jon Robbins; Manohursingh Runglall; Celia Murciano; Mariana Blagojevic; Selvam Thavaraj; Toni M Förster; Betty Hebecker; Lydia Kasper; Gema Vizcay; Simona I Iancu; Nessim Kichik; Antje Häder; Oliver Kurzai; Ting Luo; Thomas Krüger; Olaf Kniemeyer; Ernesto Cota; Oliver Bader; Robert T Wheeler; Thomas Gutsmann; Bernhard Hube; Julian R Naglik
Journal:  Nature       Date:  2016-03-30       Impact factor: 49.962
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