Literature DB >> 16177384

Identification of new antigens in visceral leishmaniasis by expression cloning and immunoblotting with sera of kala-azar patients from Bihar, India.

Stephan M Theinert1, Rajatava Basu, Michael Forgber, Syamal Roy, Shyam Sundar, Peter Walden.   

Abstract

Sera of kala-azar patients from Bihar, India, were used to identify Leishmania donovani antigens encoded by a phage expression library. Ten antigens were identified, five of which have not been described as leishmania antigens before. The antigens specifically react with sera of leishmania-infected patients but not of toxoplasma- or plasmodium-infected patients.

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Year:  2005        PMID： 16177384      PMCID： PMC1230992          DOI： 10.1128/IAI.73.10.7018-7021.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  13 in total

1.  Immunization with a recombinant stage-regulated surface protein from Leishmania donovani induces protection against visceral leishmaniasis.

Authors:  S Stäger; D F Smith; P M Kaye
Journal:  J Immunol       Date:  2000-12-15       Impact factor: 5.422

2.  Natural antibodies and complement are endogenous adjuvants for vaccine-induced CD8+ T-cell responses.

Authors:  Simona Stäger; James Alexander; Alun C Kirby; Marina Botto; Nico Van Rooijen; Deborah F Smith; Frank Brombacher; Paul M Kaye
Journal:  Nat Med       Date:  2003-09-21       Impact factor: 53.440

3.  Molecular characterization of a Leishmania donovanii cDNA clone with similarity to human 20S proteasome a-type subunit.

Authors:  C B Christensen; L Jørgensen; A T Jensen; S Gasim; M Chen; A Kharazmi; T G Theander; K Andresen
Journal:  Biochim Biophys Acta       Date:  2000-01-03

4.  Identification and characterisation of a Leishmania donovani antigen belonging to the 70-kDa heat-shock protein family.

Authors:  J MacFarlane; M L Blaxter; R P Bishop; M A Miles; J M Kelly
Journal:  Eur J Biochem       Date:  1990-06-20

5.  Genomic organization and expression of two independent gene arrays coding for two antigenic acidic ribosomal proteins of Leishmania.

Authors:  M Soto; J M Requena; M Garcia; L C Gómez; I Navarrete; C Alonso
Journal:  J Biol Chem       Date:  1993-10-15       Impact factor: 5.157

6.  Detection of Leishmania infantum cryptic infection in asymptomatic blood donors living in an endemic area (Eivissa, Balearic Islands, Spain) by different diagnostic methods.

Authors:  C Riera; R Fisa; M Udina; M Gállego; M Portus
Journal:  Trans R Soc Trop Med Hyg       Date:  2004-02       Impact factor: 2.184

7.  Isolation, characterization and analysis of the expression of the Leishmania ribosomal PO protein genes.

Authors:  M Soto; J M Requena; C Alonso
Journal:  Mol Biochem Parasitol       Date:  1993-10       Impact factor: 1.759

8.  Detection of Leishmania infantum kinetoplast DNA in peripheral blood from asymptomatic individuals at risk for parenterally transmitted infections: relationship between polymerase chain reaction results and other Leishmania infection markers.

Authors:  Joaquina Martín-Sánchez; Juan A Pineda; Francisco Morillas-Márquez; José A García-García; Carmen Acedo; Juan Macías
Journal:  Am J Trop Med Hyg       Date:  2004-05       Impact factor: 2.345

9.  Leishmania donovani: amastigote inhibition and mode of action of berberine.

Authors:  A K Ghosh; F K Bhattacharyya; D K Ghosh
Journal:  Exp Parasitol       Date:  1985-12       Impact factor: 2.011

10.  A role for IgG immune complexes during infection with the intracellular pathogen Leishmania.

Authors:  Suzanne A Miles; Sean M Conrad; Renata G Alves; Selma M B Jeronimo; David M Mosser
Journal:  J Exp Med       Date:  2005-03-07       Impact factor: 14.307
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  4 in total

Review 1.  Diagnosis of visceral leishmaniasis: developments over the last decade.

Authors:  Gurumurthy Srividya; Arpita Kulshrestha; Ruchi Singh; Poonam Salotra
Journal:  Parasitol Res       Date:  2011-11-09       Impact factor: 2.289

2.  Mapping the antigenicity of the parasites in Leishmania donovani infection by proteome serology.

Authors:  Michael Forgber; Rajatava Basu; Kaushik Roychoudhury; Stephan Theinert; Syamal Roy; Shyam Sundar; Peter Walden
Journal:  PLoS One       Date:  2006-12-20       Impact factor: 3.240

3.  Comparative Proteomic Profiling of Leishmania tropica: Investigation of a Case Infected with Simultaneous Cutaneous and Viscerotropic Leishmaniasis by 2-Dimentional Electrophoresis and Mass Spectrometry.

Authors:  Homa Hajjaran; Parisa Mousavi; Richard Burchmore; Mehdi Mohebali; Mitra Mohammadi Bazargani; Ghasem Hosseini Salekdeh; Elham Kazemi-Rad; Mohammad Reza Khoramizadeh
Journal:  Iran J Parasitol       Date:  2015 Jul-Sep       Impact factor: 1.012

4.  Identification of novel Leishmania donovani antigens that help define correlates of vaccine-mediated protection in visceral leishmaniasis.

Authors:  Sudipta Bhowmick; Nahid Ali
Journal:  PLoS One       Date:  2009-06-05       Impact factor: 3.240
  4 in total

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