Literature DB >> 16177381

Pathophysiological manifestations in mice exposed to anthrax lethal toxin.

Nathan C Culley1, David M Pinson, Anuradha Chakrabarty, Matthew S Mayo, Steven M LeVine.   

Abstract

Pathophysiological changes associated with anthrax lethal toxin included loss of plasma proteins, decreased platelet count, slower clotting times, fibrin deposits in tissue sections, and gross and histopathological evidence of hemorrhage. These findings suggest that blood vessel leakage and hemorrhage lead to disseminating intravascular coagulation and/or circulatory shock as an underlying pathophysiological mechanism.

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Year:  2005        PMID： 16177381      PMCID： PMC1230913          DOI： 10.1128/IAI.73.10.7006-7010.2005

Source DB:  PubMed          Journal:  Infect Immun        ISSN： 0019-9567            Impact factor:   3.441


  14 in total

1.  Quantitative pathology of inhalational anthrax I: quantitative microscopic findings.

Authors:  L M Grinberg; F A Abramova; O V Yampolskaya; D H Walker; J H Smith
Journal:  Mod Pathol       Date:  2001-05       Impact factor: 7.842

2.  Protection against anthrax lethal toxin challenge by genetic immunization with a plasmid encoding the lethal factor protein.

Authors:  B M Price; A L Liner; S Park; S H Leppla; A Mateczun; D R Galloway
Journal:  Infect Immun       Date:  2001-07       Impact factor: 3.441

3.  Anthrax lethal toxin induces endothelial barrier dysfunction.

Authors:  Jason M Warfel; Amber D Steele; Felice D'Agnillo
Journal:  Am J Pathol       Date:  2005-06       Impact factor: 4.307

4.  ATR/TEM8 is highly expressed in epithelial cells lining Bacillus anthracis' three sites of entry: implications for the pathogenesis of anthrax infection.

Authors:  Gloria Bonuccelli; Federica Sotgia; Philippe G Frank; Terence M Williams; Cecilia J de Almeida; Herbert B Tanowitz; Philipp E Scherer; Kylie A Hotchkiss; Bruce I Terman; Brent Rollman; Abdelkrim Alileche; Jürgen Brojatsch; Michael P Lisanti
Journal:  Am J Physiol Cell Physiol       Date:  2005-02-02       Impact factor: 4.249

5.  Fatal inhalational anthrax with unknown source of exposure in a 61-year-old woman in New York City.

Authors:  Bushra Mina; J P Dym; Frank Kuepper; Raymond Tso; Carmina Arrastia; Irina Kaplounova; Hasan Faraj; Agnieszka Kwapniewski; Christopher M Krol; Mayer Grosser; Jeffrey Glick; Steven Fochios; Athena Remolina; Ljiljana Vasovic; Jeffrey Moses; Thomas Robin; Maria DeVita; Michael L Tapper
Journal:  JAMA       Date:  2002-02-20       Impact factor: 56.272

6.  Fatal inhalational anthrax in a 94-year-old Connecticut woman.

Authors:  Lydia A Barakat; Howard L Quentzel; John A Jernigan; David L Kirschke; Kevin Griffith; Stephen M Spear; Katherine Kelley; Diane Barden; Donald Mayo; David S Stephens; Tanja Popovic; Chung Marston; Sherif R Zaki; Jeanette Guarner; Wun-Ju Shieh; H Wayne Carver; Richard F Meyer; David L Swerdlow; Eric E Mast; James L Hadler
Journal:  JAMA       Date:  2002-02-20       Impact factor: 56.272

7.  Pathology of inhalational anthrax in 42 cases from the Sverdlovsk outbreak of 1979.

Authors:  F A Abramova; L M Grinberg; O V Yampolskaya; D H Walker
Journal:  Proc Natl Acad Sci U S A       Date:  1993-03-15       Impact factor: 11.205

8.  Heme oxygenase-1 in SJL mice with experimental allergic encephalomyelitis.

Authors:  A Chakrabarty; M R Emerson; S M LeVine
Journal:  Mult Scler       Date:  2003-08       Impact factor: 6.312

9.  Pathology of inhalation anthrax in cynomolgus monkeys (Macaca fascicularis).

Authors:  Daphne Vasconcelos; Roy Barnewall; Michael Babin; Robert Hunt; James Estep; Carl Nielsen; Robert Carnes; John Carney
Journal:  Lab Invest       Date:  2003-08       Impact factor: 5.662

10.  GI anthrax: report of one case confirmed with autopsy.

Authors:  Fariborz Mansour-Ghanaei; Shahab Zareh; Arezoo Salimi
Journal:  Med Sci Monit       Date:  2002-09
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  23 in total

Review 1.  New insights into the biological effects of anthrax toxins: linking cellular to organismal responses.

Authors:  Annabel Guichard; Victor Nizet; Ethan Bier
Journal:  Microbes Infect       Date:  2011-09-08       Impact factor: 2.700

2.  A monoclonal antibody to Bacillus anthracis protective antigen defines a neutralizing epitope in domain 1.

Authors:  Johanna Rivera; Antonio Nakouzi; Nareen Abboud; Ekaterina Revskaya; David Goldman; R John Collier; Ekaterina Dadachova; Arturo Casadevall
Journal:  Infect Immun       Date:  2006-07       Impact factor: 3.441

3.  Fatal attraction: vegetation responses to nutrient inputs attract herbivores to infectious anthrax carcass sites.

Authors:  Wendy C Turner; Kyrre L Kausrud; Yathin S Krishnappa; Joris P G M Cromsigt; Holly H Ganz; Isaac Mapaure; Claudine C Cloete; Zepee Havarua; Martina Küsters; Wayne M Getz; Nils Chr Stenseth
Journal:  Proc Biol Sci       Date:  2014-11-22       Impact factor: 5.349

4.  Soluble P-selectin rescues mice from anthrax lethal toxin-induced mortality through PSGL-1 pathway-mediated correction of hemostasis.

Authors:  Der-Shan Sun; Yao-Wen Chang; Jyh-Hwa Kau; Hsin-Hsien Huang; Pei-Hsun Ho; Yin-Jeh Tzeng; Hsin-Hou Chang
Journal:  Virulence       Date:  2017-01-19       Impact factor: 5.882

5.  Anthrax lethal and edema toxins fail to directly impair human platelet function.

Authors:  Kassidy M Chauncey; Sarah E Szarowicz; Gurjit S Sidhu; Russell L During; Frederick S Southwick
Journal:  J Infect Dis       Date:  2011-12-07       Impact factor: 5.226

6.  Cutting edge: resistance to Bacillus anthracis infection mediated by a lethal toxin sensitive allele of Nalp1b/Nlrp1b.

Authors:  Jill K Terra; Christopher K Cote; Bryan France; Amy L Jenkins; Joel A Bozue; Susan L Welkos; Steven M LeVine; Kenneth A Bradley
Journal:  J Immunol       Date:  2009-11-30       Impact factor: 5.422

7.  Anthrax lethal toxin enhances IkappaB kinase activation and differentially regulates pro-inflammatory genes in human endothelium.

Authors:  Jason M Warfel; Felice D'Agnillo
Journal:  J Biol Chem       Date:  2009-07-20       Impact factor: 5.157

8.  The physiologic responses of Dutch belted rabbits infected with inhalational anthrax.

Authors:  William S Lawrence; Jason M Hardcastle; Douglas L Brining; Lori E Weaver; Cindy Ponce; Elbert B Whorton; Johnny W Peterson
Journal:  Comp Med       Date:  2009-06       Impact factor: 0.982

9.  Human serum contains a protease that protects against cytotoxic activity of Bacillus anthracis lethal toxin in vitro.

Authors:  David L Goldman; WangYong Zeng; Johanna Rivera; Antonio Nakouzzi; Arturo Casadevall
Journal:  Clin Vaccine Immunol       Date:  2008-04-30

10.  Bacillus anthracis cell wall peptidoglycan but not lethal or edema toxins produces changes consistent with disseminated intravascular coagulation in a rat model.

Authors:  Ping Qiu; Yan Li; Joseph Shiloach; Xizhong Cui; Junfeng Sun; Loc Trinh; Joanna Kubler-Kielb; Evgeny Vinogradov; Haresh Mani; Mariam Al-Hamad; Yvonne Fitz; Peter Q Eichacker
Journal:  J Infect Dis       Date:  2013-06-03       Impact factor: 5.226
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