Literature DB >> 16176187

Ulcer-free survival following management of foot ulcers in diabetes.

N Pound1, S Chipchase, K Treece, F Game, W Jeffcoate.   

Abstract

AIMS: Measures of healing rate may not give a complete indication of the effectiveness of overall management of diabetic foot ulcers. Apart from healing and speed of healing, the outcomes of greatest importance to the patient are avoidance of any amputation and remaining free from any recurrence. We have documented the number of patients presenting with diabetic foot ulcers who become ulcer free and examined the value of documenting ulcer-free survival.
METHODS: All referrals to a specialist diabetic foot clinic over a 31-month period were analysed and outcomes were determined after a minimum follow-up of 6 months.
RESULTS: Three hundred and seventy patients were referred with a total of 1031 ulcers. One hundred and twenty-one (32.7%) never became ulcer free: 56 (46.3% of 121) remained unhealed, the ulcers of 12 (9.9% of 121) had been resolved by amputation, two remained unhealed after amputation (1.7% of 121) and 51 (13.8% of 370) had died. Two hundred and thirty-one (62.4% of 370) became ulcer free at some stage. Five of these were excluded because of an earlier amputation. Ninety-one of the remaining 226 (40.3%) developed a recurrent or new ulcer after a median 126 days. Of the 135 who did not have a recurrence, 133 (58.8% of 226; 35.9% of 370) survived ulcer free and with limbs intact, while two died. Outcome was unknown in 18 (4.9%). Those who never became ulcer free were older (P < 0.001) and with a greater prevalence of ischaemia (P < 0.001). Those who healed but went on to suffer a new ulcer had a greater prevalence of neuropathy (P = 0.027) than those who remained ulcer free.
CONCLUSIONS: The use of ulcer-free survival can be used as an indication of the effectiveness of foot ulcer management. It could be adopted as a measure to compare performance between different specialist units.

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Year:  2005        PMID: 16176187     DOI: 10.1111/j.1464-5491.2005.01640.x

Source DB:  PubMed          Journal:  Diabet Med        ISSN: 0742-3071            Impact factor:   4.359


  38 in total

1.  Ulcer-free survival days and ulcer healing in patients with diabetic foot ulcers: A prospective cohort study.

Authors:  Afram Akturk; Jaap J van Netten; Rene Scheer; Marloes Vermeer; Jeff G van Baal
Journal:  Int Wound J       Date:  2019-08-19       Impact factor: 3.315

Review 2.  Dressings for treating foot ulcers in people with diabetes: an overview of systematic reviews.

Authors:  Lihua Wu; Gill Norman; Jo C Dumville; Susan O'Meara; Sally E M Bell-Syer
Journal:  Cochrane Database Syst Rev       Date:  2015-07-14

3.  Effective management of patients with diabetes foot ulcers: outcomes of an Interprofessional Diabetes Foot Ulcer Team.

Authors:  Rajna Ogrin; Pamela E Houghton; G William Thompson
Journal:  Int Wound J       Date:  2013-07-09       Impact factor: 3.315

4.  Characteristics of a large cohort of patients with diabetes having at-risk feet and outcomes in patients with foot ulceration referred to a tertiary care diabetes unit.

Authors:  Musarrat Riaz; Zahid Miyan; Syed I Zaidi; Syed Fd Alvi; Asher Fawwad; Muhammad Y Ahmadani; Asim B Zafar; Rayaz A Malik; Abdul Basit
Journal:  Int Wound J       Date:  2014-05-02       Impact factor: 3.315

Review 5.  Alginate dressings for healing diabetic foot ulcers.

Authors:  Jo C Dumville; Susan O'Meara; Sohan Deshpande; Katharine Speak
Journal:  Cochrane Database Syst Rev       Date:  2013-06-25

6.  A classification of diabetic foot infections using ICD-9-CM codes: application to a large computerized medical database.

Authors:  Benjamin G Fincke; Donald R Miller; Robin Turpin
Journal:  BMC Health Serv Res       Date:  2010-07-06       Impact factor: 2.655

7.  Patients' perspectives on foot complications in type 2 diabetes: a qualitative study.

Authors:  Lone Gale; Kavita Vedhara; Aidan Searle; Terry Kemple; Rona Campbell
Journal:  Br J Gen Pract       Date:  2008-08       Impact factor: 5.386

Review 8.  Hydrocolloid dressings for healing diabetic foot ulcers.

Authors:  Jo C Dumville; Sohan Deshpande; Susan O'Meara; Katharine Speak
Journal:  Cochrane Database Syst Rev       Date:  2013-08-06

9.  Education for secondary prevention of foot ulcers in people with diabetes: a randomised controlled trial.

Authors:  N B Lincoln; K A Radford; F L Game; W J Jeffcoate
Journal:  Diabetologia       Date:  2008-08-30       Impact factor: 10.122

Review 10.  Hyperbaric Oxygen Therapy for the Treatment of Diabetic Foot Ulcers: A Health Technology Assessment.

Authors: 
Journal:  Ont Health Technol Assess Ser       Date:  2017-05-12
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