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Literature DB >> 16175646

Chemical primer extension: efficiently determining single nucleotides in DNA.

Patrizia Hagenbuch¹, Eric Kervio, Annette Hochgesand, Ulrich Plutowski, Clemens Richert.

Abstract

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Year: 2005 PMID： 16175646 DOI： 10.1002/anie.200501794

Source DB: PubMed Journal: Angew Chem Int Ed Engl ISSN： 1433-7851 Impact factor: 15.336

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22 in total

1. Templating efficiency of naked DNA.

Authors: Eric Kervio; Annette Hochgesand; Ulrich E Steiner; Clemens Richert
Journal: Proc Natl Acad Sci U S A Date: 2010-06-16 Impact factor: 11.205

2. The effect of leaving groups on binding and reactivity in enzyme-free copying of DNA and RNA.

Authors: Eric Kervio; Marilyne Sosson; Clemens Richert
Journal: Nucleic Acids Res Date: 2016-05-27 Impact factor: 16.971

3. Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences.

Authors: Kevin Leu; Eric Kervio; Benedikt Obermayer; Rebecca M Turk-MacLeod; Caterina Yuan; Jesus-Mario Luevano; Eric Chen; Ulrich Gerland; Clemens Richert; Irene A Chen
Journal: J Am Chem Soc Date: 2012-12-21 Impact factor: 15.419

4. Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers.

Authors: Jason P Schrum; Alonso Ricardo; Mathangi Krishnamurthy; J Craig Blain; Jack W Szostak
Journal: J Am Chem Soc Date: 2009-10-14 Impact factor: 15.419

Chemical primer extension: efficiently determining single nucleotides in DNA.

1. Templating efficiency of naked DNA.

2. The effect of leaving groups on binding and reactivity in enzyme-free copying of DNA and RNA.

3. Cascade of reduced speed and accuracy after errors in enzyme-free copying of nucleic acid sequences.

4. Efficient and rapid template-directed nucleic acid copying using 2'-amino-2',3'-dideoxyribonucleoside-5'-phosphorimidazolide monomers.

5. Effect of stalling after mismatches on the error catastrophe in nonenzymatic nucleic acid replication.

6. The strength of the template effect attracting nucleotides to naked DNA.

7. Thermodynamic insights into 2-thiouridine-enhanced RNA hybridization.

8. Insight into the mechanism of nonenzymatic RNA primer extension from the structure of an RNA-GpppG complex.

9. Template-directed synthesis of a genetic polymer in a model protocell.

10. N2'-->p3' phosphoramidate glycerol nucleic acid as a potential alternative genetic system.