| Literature DB >> 16175358 |
Abstract
In order to evaluate the efficacy of linezolid for treating severe infections with coryneform bacteria, the activity of linezolid was tested in vitro against 425 clinically relevant isolates of coryneform bacteria and compared with the activity of penicillin and erythromycin. The minimal inhibitory concentration of linezolid did not exceed 2 microg/ml for any of the isolates tested, indicating that this agent has very good activity against coryneform bacteria. These results suggest linezolid is a possible alternative antimicrobial agent for the treatment of severe infections caused by coryneform bacteria.Entities:
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Year: 2005 PMID: 16175358 DOI: 10.1007/s10096-005-0014-x
Source DB: PubMed Journal: Eur J Clin Microbiol Infect Dis ISSN: 0934-9723 Impact factor: 3.267