| Literature DB >> 16175256 |
R Pal1, M Yang, R Lin, B N Johnson, N Srivastava, S Z Razzacki, K J Chomistek, D C Heldsinger, R M Haque, V M Ugaz, P K Thwar, Z Chen, K Alfano, M B Yim, M Krishnan, A O Fuller, R G Larson, D T Burke, M A Burns.
Abstract
An integrated microfluidic device capable of performing a variety of genetic assays has been developed as a step towards building systems for widespread dissemination. The device integrates fluidic and thermal components such as heaters, temperature sensors, and addressable valves to control two nanoliter reactors in series followed by an electrophoretic separation. This combination of components is suitable for a variety of genetic analyses. As an example, we have successfully identified sequence-specific hemagglutinin A subtype for the A/LA/1/87 strain of influenza virus. The device uses a compact design and mass production technologies, making it an attractive platform for a variety of widely disseminated applications.Entities:
Mesh：
Substances：
Year: 2005 PMID： 16175256 DOI： 10.1039/b505994a
Source DB: PubMed Journal: Lab Chip ISSN： 1473-0189 Impact factor: 6.799